C75.8
BillableMalignant neoplasm with pluriglandular involvement, unspecified
HCC Category Mapping
V28HCC 23 — Melanoma and Other Skin Cancers
0.251V24HCC 12 — Breast, Prostate, and Other Cancers and Tumors
0.150ESRDHCC 12 — Breast, Prostate, and Other Cancers and Tumors
0.000RxHCCHCC 22 — Cancer, Other Specified Sites
0.000What This Code Means
A malignant (cancerous) tumor involving multiple endocrine glands simultaneously, but the specific combination or primary site is not clearly specified.
Coding Tips
- •Use this code only when multiple glands are involved and the specific pattern cannot be classified elsewhere
- •Request clarification from the provider about which glands are affected to potentially use more specific codes
Clinical Significance
Malignant neoplasm with pluriglandular involvement, unspecified, represents malignancy affecting multiple endocrine glands simultaneously without further specification. This may occur in the context of multiple endocrine neoplasia (MEN) syndromes where malignant transformation occurs in more than one gland. This code requires careful clinical correlation to ensure each affected gland is also coded individually when possible.
Documentation Requirements
- ✓Documentation of malignancy involving multiple endocrine glands
- ✓Identification of each affected gland — consider coding each gland separately with its own specific code
- ✓Evaluation for MEN syndrome (MEN1, MEN2A, MEN2B) with genetic testing results
- ✓Pathology reports for each affected gland
- ✓Treatment plan addressing each site of malignancy
Commonly Confused Codes
E31.20 — Multiple endocrine neoplasia, unspecified: MEN syndrome diagnosis, not the malignancy itselfC73, C75.0, C75.1 — Individual endocrine gland malignancies: Code each specific gland separately when identifiedC75.9 — Malignant neoplasm of endocrine gland, unspecified: Single gland, unspecified; not pluriglandularE31.0 — Autoimmune polyglandular failure: Autoimmune, not neoplastic
Code Hierarchy
└C75Malignant neoplasm of other endocrine glands and related structures└C75.8Malignant neoplasm with pluriglandular involvement, unspecified
└C75.8Malignant neoplasm with pluriglandular involvement, unspecified