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C75.0 ICD-10-CM Code: Malignant neoplasm of parathyroid gland

C75.0 maps to CMS-HCC V28 23. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · free HCC coding tools

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Code lookupC75.0

FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of thyroid and other endocrine glands (C73-C75)

C75.0

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Malignant neoplasm of parathyroid gland

Cancer that develops in the parathyroid glands, four small glands in the neck that regulate calcium levels in the blood.

Buddy the Bee presenting code insight

Buddy Insight

Malignant neoplasm of the parathyroid gland is an exceedingly rare endocrine malignancy that typically presents with severe primary hyperparathyroidism and markedly elevated calcium and parathyroid hormone levels.

CMS-HCC V28

HCC 23

Coefficient HCC 23: 0.186 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 013

Code-level coefficient reference

ESRD/PACE

HCC 12

Code-level coefficient reference

RXHCC

HCC 22

Code-level coefficient reference

Inclusion Terms

Official

No inclusion terms are included in this display for C75.0. Check the code and parent instructions in the Code Book.

Excludes 2

Official

No Excludes 2 notes are included in this display for C75.0. Check the code and parent instructions in the Code Book.

Includes

Official

No Includes notes are included in this display for C75.0. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • malignant carcinoid tumors (C7A.0-)Inherited from C75
  • malignant neoplasm of adrenal gland (C74.-)Inherited from C75
  • malignant neoplasm of endocrine pancreas (C25.4)Inherited from C75
  • malignant neoplasm of islets of Langerhans (C25.4)Inherited from C75
  • malignant neoplasm of ovary (C56.-)Inherited from C75
  • malignant neoplasm of testis (C62.-)Inherited from C75
  • malignant neoplasm of thymus (C37)Inherited from C75
  • malignant neoplasm of thyroid gland (C73)Inherited from C75
  • malignant neuroendocrine tumors (C7A.-)Inherited from C75

Code First

Official

No Code First sequencing instructions are included in this display for C75.0. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for C75.0. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for C75.0. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Pathology confirming parathyroid carcinoma — histological diagnosis is challenging and often requires expert review
Calcium and parathyroid hormone levels (typically markedly elevated in carcinoma vs. adenoma)
Documentation distinguishing from parathyroid adenoma (benign) which is far more common
Staging and extent of disease including any lymph node or distant metastases

MEAT Support

HCC Buddy guidance
Pathology confirming parathyroid carcinoma — histological diagnosis is challenging and often requires expert review
Calcium and parathyroid hormone levels (typically markedly elevated in carcinoma vs. adenoma)
Documentation distinguishing from parathyroid adenoma (benign) which is far more common
Staging and extent of disease including any lymph node or distant metastases

Audit Caution

HCC Buddy guidance
Coding parathyroid adenoma as carcinoma — adenomas are far more common and are benign
Confusing parathyroid carcinoma with thyroid carcinoma due to anatomical proximity
Not coding associated hypercalcemia (E83.52) and hyperparathyroidism (E21.0) when documented
Failing to distinguish primary parathyroid malignancy from metastatic disease to the parathyroid region

Common Mistakes

HCC Buddy guidance
D35.1 — Benign neoplasm of parathyroid gland: Parathyroid adenomas are benign and much more common
E21.0 — Primary hyperparathyroidism: Hormonal condition caused by the tumor; code both when applicable
E83.52 — Hypercalcemia: A manifestation of the parathyroid malignancy; code additionally when documented
C73 — Malignant neoplasm of thyroid gland: Adjacent anatomy; verify parathyroid vs. thyroid origin

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C75.0 an HCC code?

Yes. C75.0 (Malignant neoplasm of parathyroid gland) maps to HCC 23, Prostate, Breast, and Other Cancers and Tumors under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 0.186. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: C75.0 is billable and maps to V28 HCC 23, Prostate, Breast, and Other Cancers and Tumors. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
C75.0
Description
Malignant neoplasm of parathyroid gland
HCC (V28)
HCC 23 — Prostate, Breast, and Other Cancers and Tumors
RAF reference coefficient
0.186
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 23, Prostate, Breast, and Other Cancers and Tumors
0.186
ESRDHCC 12, Breast/Prostate/and Other Cancers and Tumors
Not separately weighted
RxHCCHCC 22, Prostate, Breast, Bladder, and Other Cancers and Tumors
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work C75.0 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for C75.0

For C75.0, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

C75.0 is the ICD-10-CM diagnosis code for malignant neoplasm of parathyroid gland. Cancer that develops in the parathyroid glands, four small glands in the neck that regulate calcium levels in the blood. C75.0 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of thyroid and other endocrine glands (c73-c75).

Under the CMS-HCC V28 risk adjustment model, C75.0 maps to Prostate, Breast, and Other Cancers and Tumors (HCC 23) with a source-labeled community, non-dual, aged reference coefficient of 0.186. No V24 mapping is shown for C75.0; use the applicable model and payment year when reviewing the V28 mapping. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Parathyroid carcinoma is rare; ensure documentation confirms malignancy and not benign parathyroid adenoma (which would be coded differently). For C75.0, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C75.0 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Parathyroid carcinoma is rare; ensure documentation confirms malignancy and not benign parathyroid adenoma (which would be coded differently)
  • Verify whether single or multiple parathyroid glands are involved, as this may affect staging and treatment decisions

Clinical Significance

Malignant neoplasm of the parathyroid gland is an exceedingly rare endocrine malignancy that typically presents with severe primary hyperparathyroidism and markedly elevated calcium and parathyroid hormone levels. Parathyroid carcinoma accounts for less than 1% of primary hyperparathyroidism cases, making accurate diagnosis and coding critical for treatment planning and surveillance.

Documentation Requirements

  • Pathology confirming parathyroid carcinoma — histological diagnosis is challenging and often requires expert review
  • Calcium and parathyroid hormone levels (typically markedly elevated in carcinoma vs. adenoma)
  • Documentation distinguishing from parathyroid adenoma (benign) which is far more common
  • Staging and extent of disease including any lymph node or distant metastases
  • Treatment status (surgical resection, monitoring of calcium levels)

Commonly Confused Codes

  • D35.1: Benign neoplasm of parathyroid gland: Parathyroid adenomas are benign and much more common
  • E21.0: Primary hyperparathyroidism: Hormonal condition caused by the tumor; code both when applicable
  • E83.52: Hypercalcemia: A manifestation of the parathyroid malignancy; code additionally when documented
  • C73: Malignant neoplasm of thyroid gland: Adjacent anatomy; verify parathyroid vs. thyroid origin
  • D44.2: Neoplasm of uncertain behavior of parathyroid gland: Use when malignancy is not confirmed

Child Codes

Code Hierarchy

Also searched as

  • C75 0
  • C750

For C75.0, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

C75.0 maps to CMS-HCC V28 category 23, Prostate, Breast, and Other Cancers and Tumors. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. The mapping identifies a payment HCC category for C75.0. Review its source-labeled HCC coefficient above, check the RAF Calculator with complete member context for CMS-HCC V28 PY2026, and confirm the documentation the chart needs before the code is submitted. HCC Buddy shows no RAF score unless every required source and calculation check passes.

Work C75.0 in HCC Buddy

Open C75.0 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.