C60.0
BillableMalignant neoplasm of prepuce
HCC Category Mapping
V28HCC 23 — Melanoma and Other Skin Cancers
0.251V24HCC 12 — Breast, Prostate, and Other Cancers and Tumors
0.150ESRDHCC 12 — Breast, Prostate, and Other Cancers and Tumors
0.000RxHCCHCC 22 — Cancer, Other Specified Sites
0.000What This Code Means
Cancer that starts in the foreskin (prepuce) of the penis. This is a malignant tumor affecting the tissue that covers the head of the penis.
Coding Tips
- •Verify documentation specifies the prepuce as the primary site to distinguish from other penile locations
- •Ensure laterality is not applicable for this code as it refers to a specific anatomical structure
Clinical Significance
Malignant neoplasm of the prepuce (foreskin) is a specific subsite of penile cancer, most commonly squamous cell carcinoma. Risk factors include lack of circumcision, phimosis, HPV infection, and poor hygiene. Accurate subsite documentation within the penis is essential for treatment planning (organ-sparing surgery vs. partial penectomy) and proper risk adjustment coding.
Documentation Requirements
- ✓Pathology confirming malignancy of the prepuce/foreskin specifically
- ✓Histologic type (squamous cell carcinoma in majority of cases)
- ✓TNM staging and grade
- ✓HPV status if tested
- ✓Extent of local invasion and lymph node involvement
- ✓Circumcision status
Commonly Confused Codes
C60.1 — Glans penis cancer; the prepuce covers the glans but is a separate anatomical siteC60.2 — Body of penis; shaft cancer is coded differently from foreskin cancerC60.9 — Penis unspecified; always use C60.0 when prepuce is specifically documentedD29.0 — Benign neoplasm of penis; confirm malignancy before assigning C60 codes
Code Hierarchy
└C60Malignant neoplasm of penis└C60.0Malignant neoplasm of prepuce
└C60.0Malignant neoplasm of prepuce