B97.35
BillableHuman immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere
HCC Category Mapping
V28HCC 1 — HIV/AIDS
0.309V24HCC 1 — HIV/AIDS
0.311ESRDHCC 1 — HIV/AIDS
0.000RxHCCHCC 1 — HIV/AIDS
0.000What This Code Means
Human immunodeficiency virus type 2 (HIV-2) is identified as the underlying cause of another disease or condition being treated.
Coding Tips
- •This code is used when HIV-2 (rather than HIV-1) is the causative agent; pair with the primary diagnosis code for the opportunistic infection or AIDS-related condition
- •HIV-2 is less common than HIV-1 but follows similar coding principles with secondary code usage
Clinical Significance
HIV-2 as cause of disease classified elsewhere identifies the specific viral strain when HIV-2 is the underlying etiology. HIV-2 is less common globally than HIV-1 and is primarily found in West Africa. It progresses more slowly and is inherently resistant to non-nucleoside reverse transcriptase inhibitors, making identification critical for treatment selection. This code maps to the highest-tier HIV/AIDS HCC.
Documentation Requirements
- ✓Confirmatory HIV-2 serologic testing (HIV-2 specific Western blot or differentiation assay)
- ✓Documentation that the infection is specifically HIV-2, not HIV-1 or dual infection
- ✓The primary manifestation/condition being caused by HIV-2 must also be coded
- ✓Current antiretroviral regimen documented (noting NNRTI resistance)
- ✓CD4 count and HIV-2 viral load if available
Commonly Confused Codes
B20 (HIV disease resulting in infectious and parasitic diseases) - B20 is used for symptomatic HIV disease as the primary diagnosis; B97.35 is the supplementary causative agent codeZ21 (Asymptomatic HIV infection status) - use for asymptomatic HIV, not as a causative agent codeB97.33 (HIV-1 as the cause) - different strain; HIV-2 has different treatment implications and drug resistance
Code Hierarchy
└B97Viral agents as the cause of diseases classified elsewhere└B97.3Retrovirus as the cause of diseases classified elsewhere└B97.35Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere
└B97.35Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere