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B08.22 ICD-10-CM Code: Exanthema subitum [sixth disease] due to human herpesvirus 7

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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Viral infections characterized by skin and mucous membrane lesions (B00-B09)

B08.22

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Exanthema subitum [sixth disease] due to human herpesvirus 7

Exanthema subitum, also known as sixth disease, is a viral infection caused by human herpesvirus 7 that primarily affects infants and young children, characterized by high fever followed by a distinctive pink rash that appears as the fever subsides. This is a self-limiting condition that typically resolves without complications.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
B08Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified
B08.2Exanthema subitum [sixth disease]
B08.22Exanthema subitum [sixth disease] due to human herpesvirus 7

Inclusion Terms

Official
  • Roseola infantum due to human herpesvirus 7

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for B08.22 in this effective period.

Related Child Codes

Official
B08.20Exanthema subitum [sixth disease], unspecified
B08.21Exanthema subitum [sixth disease] due to human herpesvirus 6

Includes

Official

ICD-10-CM does not list Includes notes for B08.22 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for B08.22 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for B08.22 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for B08.22 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for B08.22 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Ensure documentation clearly specifies that human herpesvirus 7 (HHV-7) is the causative agent, as B08.21 is used for HHV-6 and B08.22 is specific to HHV-7
This code should only be assigned when the rash (exanthema subitum) is present; if only fever without the characteristic rash is documented, consider alternative coding

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is B08.22 an HCC code?

No. B08.22 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

B08.22 is the ICD-10-CM diagnosis code for exanthema subitum [sixth disease] due to human herpesvirus 7. Exanthema subitum, also known as sixth disease, is a viral infection caused by human herpesvirus 7 that primarily affects infants and young children, characterized by high fever followed by a distinctive pink rash that appears as the fever subsides. This is a self-limiting condition that typically resolves without complications. B08.22 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering viral infections characterized by skin and mucous membrane lesions (b00-b09).

B08.22 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Ensure documentation clearly specifies that human herpesvirus 7 (HHV-7) is the causative agent, as B08.21 is used for HHV-6 and B08.22 is specific to HHV-7.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for B08.22 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Ensure documentation clearly specifies that human herpesvirus 7 (HHV-7) is the causative agent, as B08.21 is used for HHV-6 and B08.22 is specific to HHV-7
  • This code should only be assigned when the rash (exanthema subitum) is present; if only fever without the characteristic rash is documented, consider alternative coding

Child Codes

Code Hierarchy

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