What is ICD-10 code B00.7?

B00.7 is the ICD-10-CM diagnosis code for Disseminated herpesviral disease. Herpes simplex virus that has spread throughout the body affecting multiple organ systems, representing a serious systemic infection. It belongs to the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99). B00.7 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. B00.7 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. B00.7 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. B00.7 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

What is the V28 vs V24 difference for B00.7?

CMS phased in the V28 risk adjustment model over payment years 2024 (33%), 2025 (67%), and 2026 (100%), replacing V24. V28 consolidates HCC categories, removes some lower-acuity conditions, and recalibrates RAF weights across the entire model. For B00.7, V28 maps to Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock at RAF 0.500 while V24 mapped to Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock at RAF 0.352. Both models can still appear in legacy data and in payer-specific lookback periods.

What should coders know when reporting B00.7?

This code indicates widespread dissemination; document which organs are involved for complete clinical picture Often requires additional codes to specify affected sites (CNS, liver, etc.) Because B00.7 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

2026 ICD-10-CM B00.7: Disseminated herpesviral

ICD-10-CM Code View

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Code lookupB00.7Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Viral infections characterized by skin and mucous membrane lesions (B00-B09)

B00.7

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Disseminated herpesviral disease

Herpes simplex virus that has spread throughout the body affecting multiple organ systems, representing a serious systemic infection.

Buddy Insight

Disseminated herpesviral disease represents systemic spread of herpes simplex virus beyond its typical mucocutaneous distribution, indicating severe immunocompromise or neonatal vulnerability.

CMS-HCC V28

Mapped

HCC 2

Septicemia, Sepsis, Systemic ...

RAF 0.500

CMS-HCC V24

Mapped

HCC 2

Septicemia, Sepsis, Systemic ...

RAF 0.352

ACA/HHS

Mapped

HCC 2

HHS-HCC 2

Varies by metal level

ESRD/PACE

Mapped

HCC 2

Septicemia, Sepsis, Systemic ...

RAF 0.087

RXHCC

N/A

—

Not risk-adjusted for this model/period.

Not mapped

Code Book Path

Official

B00Herpesviral [herpes simplex] infections

B00.7Disseminated herpesviral disease

Inclusion Terms

Official

Herpesviral sepsis

Excludes 2

Official

anogenital herpesviral infection (A60.-)
gammaherpesviral mononucleosis (B27.0-)
herpangina (B08.5)

Related Child Codes

Official

B00.0Eczema herpeticum

B00.1Herpesviral vesicular dermatitis

B00.2Herpesviral gingivostomatitis and pharyngotonsillitis

B00.3Herpesviral meningitis

B00.4Herpesviral encephalitis

Includes

Official

ICD-10-CM does not list Includes notes for B00.7 in this effective period.

Excludes 1

Official

congenital herpesviral infections (P35.2)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for B00.7 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for B00.7 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for B00.7 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance

Confirmed HSV by viral culture, PCR, or direct fluorescent antibody from affected sites

Multi-organ involvement documented (which organs: liver, CNS, lungs, adrenals, skin)

Immunocompromised status documented if applicable (HIV, transplant, chemotherapy, neonatal)

Viral type specified if known (HSV-1 or HSV-2)

MEAT Support

HCC Buddy guidance

Confirmed HSV by viral culture, PCR, or direct fluorescent antibody from affected sites

Multi-organ involvement documented (which organs: liver, CNS, lungs, adrenals, skin)

Immunocompromised status documented if applicable (HIV, transplant, chemotherapy, neonatal)

Viral type specified if known (HSV-1 or HSV-2)

Audit Caution

HCC Buddy guidance

Coding localized herpes (B00.1-B00.5) when the infection has actually disseminated to multiple organs

Not coding the underlying immunodeficiency that predisposed to dissemination

Using sepsis codes instead of the specific disseminated herpesviral disease code

Missing neonatal disseminated herpes (P35.2) in newborns — different code for perinatal acquisition

Common Mistakes

HCC Buddy guidance

B00.1 (Herpesviral vesicular dermatitis) — Localized skin herpes; disseminated disease involves multiple organ systems beyond skin

B00.4 (Herpesviral encephalitis) — HSV encephalitis is a single-organ manifestation; disseminated disease affects multiple organs

A41.9 (Sepsis, unspecified organism) — Disseminated HSV may present like sepsis but has a specific code; do not use generic sepsis codes when HSV is confirmed

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is B00.7 an HCC code?

Yes. B00.7 (Disseminated herpesviral disease) maps to Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock under the CMS-HCC V28 risk adjustment model (and Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock under V24), with a community non-dual aged RAF of 0.500. It is billable for payment year 2026.

Coder answer: B00.7 is billable and maps to V28 HCC 2, Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code: B00.7
Description: Disseminated herpesviral disease
HCC (V28): HCC 2 — Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock
RAF: 0.500
Billable: Yes
Payment year: 2026

HCC Category Mapping

V28HCC 2, Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock

0.500

V24HCC 2, Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock

0.352

ESRDHCC 2, Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock

0.087

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work B00.7 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for B00.7

For B00.7 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed B00.7 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

B00.7 is the ICD-10-CM diagnosis code for disseminated herpesviral disease. Herpes simplex virus that has spread throughout the body affecting multiple organ systems, representing a serious systemic infection. B00.7 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering viral infections characterized by skin and mucous membrane lesions (b00-b09).

Under the CMS-HCC V28 risk adjustment model, B00.7 maps to Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock (HCC 2) with a community, non-dual, aged base RAF weight of 0.500. Under the older V24 model, B00.7 mapped to the same category but with a base RAF weight of 0.352, V28 recalibrated weights across the entire model. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This code indicates widespread dissemination; document which organs are involved for complete clinical picture. Because B00.7 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for B00.7 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•This code indicates widespread dissemination; document which organs are involved for complete clinical picture
•Often requires additional codes to specify affected sites (CNS, liver, etc.)

Clinical Significance

Disseminated herpesviral disease represents systemic spread of herpes simplex virus beyond its typical mucocutaneous distribution, indicating severe immunocompromise or neonatal vulnerability. This is a life-threatening condition with multi-organ involvement that carries high mortality and maps to the high-weight sepsis HCC category.

Documentation Requirements

✓Confirmed HSV by viral culture, PCR, or direct fluorescent antibody from affected sites
✓Multi-organ involvement documented (which organs: liver, CNS, lungs, adrenals, skin)
✓Immunocompromised status documented if applicable (HIV, transplant, chemotherapy, neonatal)
✓Viral type specified if known (HSV-1 or HSV-2)
✓Severity indicators: ICU admission, organ failure, antiviral therapy regimen

Commonly Confused Codes

•B00.1 (Herpesviral vesicular dermatitis): Localized skin herpes; disseminated disease involves multiple organ systems beyond skin
•B00.4 (Herpesviral encephalitis): HSV encephalitis is a single-organ manifestation; disseminated disease affects multiple organs
•A41.9 (Sepsis, unspecified organism): Disseminated HSV may present like sepsis but has a specific code; do not use generic sepsis codes when HSV is confirmed