A52.8 ICD-10-CM Code: Late syphilis, latent
A52.8 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC Buddy coding tools
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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Infections with a predominantly sexual mode of transmission (A50-A64)
A52.8
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceLate syphilis, latent
This code describes syphilis in its late stage where the infection is present in the body but not causing active symptoms or signs. The person has been infected for more than 2 years but shows no clinical manifestations of the disease.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
Official- Syphilis (acquired) without clinical manifestations, with positive serological reaction and negative spinal fluid test, two years or more after infection
Excludes 2
Official- carrier or suspected carrier of infectious disease (Z22.-)Inherited from A00-B99, A50-A64
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)Inherited from A00-B99, A50-A64
- infectious and parasitic diseases specific to the perinatal period (P35-P39)Inherited from A00-B99, A50-A64
- influenza and other acute respiratory infections (J00-J22)Inherited from A00-B99, A50-A64
- human immunodeficiency virus [HIV] disease (B20)Inherited from A00-B99, A50-A64
Related Codes
Includes
Official- diseases generally recognized as communicable or transmissibleInherited from A00-B99
Excludes 1
Official- certain localized infections - see body system-related chaptersInherited from A00-B99, A50-A64
- nonspecific and nongonococcal urethritis (N34.1)Inherited from A00-B99, A50-A64
- Reiter's disease (M02.3-)Inherited from A00-B99, A50-A64
Code First
OfficialNo Code First sequencing instructions are included in this display for A52.8. Check the code and parent instructions in the Code Book.
Use Additional
Official- code to identify resistance to antimicrobial drugs (Z16.-)Inherited from A00-B99
Code Also
OfficialNo Code Also instructions are included in this display for A52.8. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is A52.8 an HCC code?
No. A52.8 is a billable ICD-10-CM code with no mapping under the CMS-HCC V28 or V24 community payment models, and none under the ESRD, Part D RxHCC, or HHS-HCC models.
- Code
- A52.8
- Description
- Late syphilis, latent
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A52.8 is the ICD-10-CM diagnosis code for late syphilis, latent. This code describes syphilis in its late stage where the infection is present in the body but not causing active symptoms or signs. The person has been infected for more than 2 years but shows no clinical manifestations of the disease. A52.8 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering infections with a predominantly sexual mode of transmission (a50-a64).
A52.8 is a billable ICD-10-CM code, but the current payload does not show a mapping under the CMS-HCC V28 or V24 community payment models, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.
Verify documentation specifies 'late' syphilis and 'latent' status - do not use this code for early latent syphilis (A51.41) or if active symptoms are present.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for A52.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Verify documentation specifies 'late' syphilis and 'latent' status - do not use this code for early latent syphilis (A51.41) or if active symptoms are present
- •This code requires confirmation through serological testing (positive RPR/VDRL or treponemal test) even though the patient is asymptomatic, as latent syphilis is diagnosed by lab findings rather than clinical presentation