A52.2
BillableAsymptomatic neurosyphilis
Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)
Is A52.2 an HCC code?
No. A52.2 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A52.2 is the ICD-10-CM diagnosis code for asymptomatic neurosyphilis. This is a condition where a person has syphilis bacteria in their nervous system and cerebrospinal fluid, but they don't currently have any symptoms or signs of neurological disease. It's detected through testing rather than patient complaints. A52.2 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering infections with a predominantly sexual mode of transmission (a50-a64).
A52.2 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Asymptomatic neurosyphilis requires documented evidence of CNS involvement (positive CSF serology or other confirmatory testing) without clinical neurological symptoms to distinguish it from latent syphilis.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A52.2 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Asymptomatic neurosyphilis requires documented evidence of CNS involvement (positive CSF serology or other confirmatory testing) without clinical neurological symptoms to distinguish it from latent syphilis
- •This code should be used only when neurosyphilis is confirmed; if only serological evidence of syphilis exists without CNS involvement confirmation, use the appropriate latent syphilis code instead