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A52.12 ICD-10-CM Code: Other cerebrospinal syphilis

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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Infections with a predominantly sexual mode of transmission (A50-A64)

A52.12

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other cerebrospinal syphilis

This code describes syphilis that has spread to the brain and spinal cord, causing inflammation and damage to these structures, but is not the typical form of neurosyphilis. It represents a serious stage of untreated syphilis where the infection has invaded the central nervous system.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
A52Late syphilis
A52.1Symptomatic neurosyphilis
A52.12Other cerebrospinal syphilis

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for A52.12 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for A52.12 in this effective period.

Related Child Codes

Official
A52.10Symptomatic neurosyphilis, unspecified
A52.11Tabes dorsalis
A52.13Late syphilitic meningitis
A52.14Late syphilitic encephalitis
A52.15Late syphilitic neuropathy

Includes

Official

ICD-10-CM does not list Includes notes for A52.12 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for A52.12 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for A52.12 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for A52.12 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for A52.12 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
This code is used for cerebrospinal syphilis presentations other than general paresis or tabes dorsalis; verify the clinical documentation specifies the type of CNS involvement
Ensure the syphilis stage is confirmed as secondary or tertiary before coding; this code requires evidence of CNS involvement documented in the medical record

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is A52.12 an HCC code?

No. A52.12 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

A52.12 is the ICD-10-CM diagnosis code for other cerebrospinal syphilis. This code describes syphilis that has spread to the brain and spinal cord, causing inflammation and damage to these structures, but is not the typical form of neurosyphilis. It represents a serious stage of untreated syphilis where the infection has invaded the central nervous system. A52.12 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering infections with a predominantly sexual mode of transmission (a50-a64).

A52.12 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

This code is used for cerebrospinal syphilis presentations other than general paresis or tabes dorsalis; verify the clinical documentation specifies the type of CNS involvement.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A52.12 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This code is used for cerebrospinal syphilis presentations other than general paresis or tabes dorsalis; verify the clinical documentation specifies the type of CNS involvement
  • Ensure the syphilis stage is confirmed as secondary or tertiary before coding; this code requires evidence of CNS involvement documented in the medical record

Child Codes

Code Hierarchy

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