A51.49 ICD-10-CM Code: Other secondary syphilitic conditions
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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Infections with a predominantly sexual mode of transmission (A50-A64)
A51.49
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceOther secondary syphilitic conditions
This code describes various secondary syphilis manifestations that don't fit into other specific categories, occurring weeks to months after the initial infection when the bacteria has spread throughout the body. These can include skin rashes, mucous patches, condylomas, or other systemic symptoms beyond the primary chancre.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
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Code Book Path
Inclusion Terms
Official- Secondary syphilitic lymphadenopathy
- Secondary syphilitic myositis
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for A51.49 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for A51.49 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for A51.49 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for A51.49 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for A51.49 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for A51.49 in this effective period.
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is A51.49 an HCC code?
No. A51.49 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A51.49 is the ICD-10-CM diagnosis code for other secondary syphilitic conditions. This code describes various secondary syphilis manifestations that don't fit into other specific categories, occurring weeks to months after the initial infection when the bacteria has spread throughout the body. These can include skin rashes, mucous patches, condylomas, or other systemic symptoms beyond the primary chancre. A51.49 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering infections with a predominantly sexual mode of transmission (a50-a64).
A51.49 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Use this code only when the secondary syphilitic condition is not better described by more specific A51 subcodes (such as A51.41 for secondary syphilitic meningitis or A51.43 for secondary syphilitic oculopathy).
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A51.49 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Use this code only when the secondary syphilitic condition is not better described by more specific A51 subcodes (such as A51.41 for secondary syphilitic meningitis or A51.43 for secondary syphilitic oculopathy)
- •Always verify documentation clearly indicates secondary syphilis stage and obtain specifics about which body systems are affected to determine if a more specific code applies