A50.41 ICD-10-CM Code: Late congenital syphilitic meningitis
A50.41 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software
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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Infections with a predominantly sexual mode of transmission (A50-A64)
A50.41
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceLate congenital syphilitic meningitis
This is a serious brain infection caused by syphilis that was passed from mother to child before birth and develops later in childhood or adulthood. The infection causes inflammation of the protective membranes surrounding the brain and spinal cord.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
MappedHCC 003
Code-level coefficient reference
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialNo inclusion terms are included in this display for A50.41. Check the code and parent instructions in the Code Book.
Excludes 2
Official- carrier or suspected carrier of infectious disease (Z22.-)Inherited from A00-B99, A50-A64
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)Inherited from A00-B99, A50-A64
- infectious and parasitic diseases specific to the perinatal period (P35-P39)Inherited from A00-B99, A50-A64
- influenza and other acute respiratory infections (J00-J22)Inherited from A00-B99, A50-A64
- human immunodeficiency virus [HIV] disease (B20)Inherited from A00-B99, A50-A64
Related Codes
Includes
Official- diseases generally recognized as communicable or transmissibleInherited from A00-B99
Excludes 1
Official- certain localized infections - see body system-related chaptersInherited from A00-B99, A50-A64, A50.4
- nonspecific and nongonococcal urethritis (N34.1)Inherited from A00-B99, A50-A64, A50.4
- Reiter's disease (M02.3-)Inherited from A00-B99, A50-A64, A50.4
- Hutchinson's triad (A50.53)Inherited from A00-B99, A50-A64, A50.4
Code First
OfficialNo Code First sequencing instructions are included in this display for A50.41. Check the code and parent instructions in the Code Book.
Use Additional
Official- code to identify resistance to antimicrobial drugs (Z16.-)Inherited from A00-B99, A50.4
- code to identify any associated mental disorderInherited from A00-B99, A50.4
Code Also
OfficialNo Code Also instructions are included in this display for A50.41. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is A50.41 an HCC code?
A50.41 has no mapping under the current CMS-HCC V28 community payment model. A50.41 also appears in the HHS-HCC commercial risk model (HCC 003 (HHS-HCC 003 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.
- Code
- A50.41
- Description
- Late congenital syphilitic meningitis
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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What This Code Means
A50.41 is the ICD-10-CM diagnosis code for late congenital syphilitic meningitis. This is a serious brain infection caused by syphilis that was passed from mother to child before birth and develops later in childhood or adulthood. The infection causes inflammation of the protective membranes surrounding the brain and spinal cord. A50.41 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering infections with a predominantly sexual mode of transmission (a50-a64).
A50.41 has no mapping under the current CMS-HCC V28 community payment model. A50.41 also appears in the HHS-HCC commercial risk model (HCC 003 (HHS-HCC 003 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.
This code is used only for late manifestations of congenital syphilis (typically after age 2 years); ensure documentation confirms the syphilis was acquired congenitally, not through other means.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for A50.41 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •This code is used only for late manifestations of congenital syphilis (typically after age 2 years); ensure documentation confirms the syphilis was acquired congenitally, not through other means
- •Verify that meningitis is specifically documented as the manifestation; if other late congenital syphilis complications are present, additional codes may be needed

