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FY2027 ICD-10-CM reference

F19.288: Other psychoactive substance dependence with other psychoactive substance-induced disorder

By the HCC Buddy Coding Team

The official ICD-10-CM descriptor is Other psychoactive substance dependence with other psychoactive substance-induced disorder. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Billable code. Verified against the official FY2027 order file.

CMS-HCC V28

  • HCC 137: Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications · RAF 0.424, Community Non-Dual Aged (CNA)

Payment year 2027, 2026 dates of service. HCC from the CMS 2027 Initial ICD-10-CM Mappings; RAF from the CMS-HCC V28 relative factors. For 2027 dates of service, CMS has not yet published the payment year 2028 mappings.

CMS-HCC V24

Not used for payment year 2027 Medicare Advantage payment

ESRD

Source verification pending

PACE

Source verification pending

RxHCC

Source verification pending

HHS-HCC

Source verification pending

FY2027 Tabular instructions

Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.

Includes

disorders of psychological development

Source: F01-F99 (chapter, inherited).

Excludes2

symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)

Source: F01-F99 (chapter, inherited).

Includes

polysubstance drug use (indiscriminate drug use)

Source: F19 (category, inherited).

Excludes1

other psychoactive substance abuse (F19.1-)

Source: F19.2 (self, inherited).

Excludes1

other psychoactive substance use, unspecified (F19.9-)

Source: F19.2 (self, inherited).

Instructional note

Other (or unknown) substance use disorder, moderate, with other (or unknown) substance induced mild neurocognitive disorder

Source: F19.288 (self, direct).

Instructional note

Other (or unknown) substance use disorder, severe, with other (or unknown) substance induced mild neurocognitive disorder

Source: F19.288 (self, direct).

Instructional note

Other (or unknown) substance use disorder, moderate, with other (or unknown) substance induced obsessive compulsive or related disorder

Source: F19.288 (self, direct).

Instructional note

Other (or unknown) substance use disorder, severe, with other (or unknown) substance induced obsessive-compulsive or related disorder

Source: F19.288 (self, direct).

Source: CMS FY2027 Tabular List and Alphabetic Index.

Open Tabular instructions and code details

Compare the FY2027 additions, removals and billable-status changes

What does F19.288 mean in FY2027?

The official ICD-10-CM descriptor is Other psychoactive substance dependence with other psychoactive substance-induced disorder. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Is F19.288 billable in FY2027?

The FY2027 order file marks F19.288 as billable. Check the complete Tabular instructions and documentation before assigning it.

Does F19.288 map to an HCC?

In the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service), F19.288 maps to CMS-HCC V28 HCC 137 (Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications). For 2027 dates of service, CMS has not yet published the payment year 2028 mappings. ESRD, RxHCC, PACE and HHS-HCC mappings are still pending verification for FY2027.

Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.

Review the FY2026 April edition