F12.280 ICD-10-CM Code: Cannabis dependence with cannabis-induced anxiety disorder
F12.280 maps to CMS-HCC V28 137. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · HCC Buddy coding tools
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FY 2026 Apr update / Mental, Behavioral and Neurodevelopmental disorders (F01-F99) / Mental and behavioral disorders due to psychoactive substance use (F10-F19)
F12.280
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceCannabis dependence with cannabis-induced anxiety disorder
A person who is dependent on cannabis and experiences anxiety disorder as a direct result of their cannabis use.

Buddy Insight
Cannabis dependence with cannabis-induced anxiety disorder captures a patient who meets criteria for cannabis dependence and has developed a clinically significant anxiety disorder as a direct result of cannabis use.
CMS-HCC V28
MappedHCC 137
Code-level coefficient reference
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
MappedHCC 082
Code-level coefficient reference
ESRD/PACE
MappedHCC 55
Code-level coefficient reference
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialNo inclusion terms are included in this display for F12.280. Check the code and parent instructions in the Code Book.
Excludes 2
Official- symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)Inherited from F01-F99, F12.2
- cannabis poisoning (T40.7-)Inherited from F01-F99, F12.2
Related Codes
Includes
Official- disorders of psychological developmentInherited from F01-F99, F12
- marijuanaInherited from F01-F99, F12
Excludes 1
Official- cannabis abuse (F12.1-)Inherited from F12.2
- cannabis use, unspecified (F12.9-)Inherited from F12.2
Code First
OfficialNo Code First sequencing instructions are included in this display for F12.280. Check the code and parent instructions in the Code Book.
Use Additional
OfficialNo Use Additional Code instructions are included in this display for F12.280. Check the code and parent instructions in the Code Book.
Code Also
OfficialNo Code Also instructions are included in this display for F12.280. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is F12.280 an HCC code?
Yes. F12.280 (Cannabis dependence with cannabis-induced anxiety disorder) maps to HCC 137, Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 0.424. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.
Coder answer: F12.280 is billable and maps to V28 HCC 137, Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.
- Code
- F12.280
- Description
- Cannabis dependence with cannabis-induced anxiety disorder
- HCC (V28)
- HCC 137 — Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
- RAF reference coefficient
- 0.424
- Billable
- Yes
- Payment year
- 2026
HCC Category Mapping
These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.
Work F12.280 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →
MEAT review for F12.280
For F12.280, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Coder workflow notes
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What This Code Means
F12.280 is the ICD-10-CM diagnosis code for cannabis dependence with cannabis-induced anxiety disorder. A person who is dependent on cannabis and experiences anxiety disorder as a direct result of their cannabis use. F12.280 sits in the ICD-10-CM chapter for mental, behavioral and neurodevelopmental disorders (f01-f99), within the section covering mental and behavioral disorders due to psychoactive substance use (f10-f19).
Under the CMS-HCC V28 risk adjustment model, F12.280 maps to Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications (HCC 137) with a source-labeled community, non-dual, aged reference coefficient of 0.424. No V24 mapping is shown for F12.280; use the applicable model and payment year when reviewing the V28 mapping. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.
This code requires documentation of both cannabis dependence AND cannabis-induced anxiety; do not use if anxiety exists independently. For F12.280, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for F12.280 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •This code requires documentation of both cannabis dependence AND cannabis-induced anxiety; do not use if anxiety exists independently
- •Verify in the clinical record that the anxiety disorder is temporally related to cannabis use and not a pre-existing condition
Clinical Significance
Cannabis dependence with cannabis-induced anxiety disorder captures a patient who meets criteria for cannabis dependence and has developed a clinically significant anxiety disorder as a direct result of cannabis use. This combination reflects dual psychiatric morbidity and often complicates treatment because the anxiety may both drive and result from continued cannabis use. Appropriate documentation supports both clinical care and accurate risk stratification.
Documentation Requirements
- ✓Documentation of cannabis dependence criteria
- ✓Specific anxiety symptoms (generalized anxiety, panic attacks, social anxiety, etc.)
- ✓Clinical statement that anxiety disorder is induced by cannabis use
- ✓Temporal relationship between cannabis use and anxiety
- ✓Exclusion of primary anxiety disorders that exist independently of cannabis use
- ✓Assessment of the interplay between dependence and anxiety in the treatment plan
Commonly Confused Codes
- •F12.180: Cannabis abuse with cannabis-induced anxiety disorder; use when only abuse is documented
- •F12.980: Cannabis use, unspecified with anxiety disorder; use when severity of use disorder is unspecified
- •F41.1: Generalized anxiety disorder; use for primary anxiety not substance-induced
- •F12.20: Cannabis dependence, uncomplicated; use when no anxiety disorder is present

