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E88.3

Billable

Tumor lysis syndrome

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

A serious metabolic emergency that occurs when cancer cells die rapidly, releasing their contents into the bloodstream and causing dangerous chemical imbalances.

Coding Tips

  • •This is typically an acute complication; code the underlying malignancy separately
  • •Document the trigger (chemotherapy, radiation, or spontaneous tumor breakdown) and any associated acute kidney injury or electrolyte abnormalities

Use Additional Code

  • code for adverse effect, if applicable, to identify drug (T45.1X5)

Code Hierarchy

└E88Other and unspecified metabolic disorders└E88.3Tumor lysis syndrome
└E88.3Tumor lysis syndrome

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