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E24.8 ICD-10-CM Code: Other Cushing's syndrome

ICD-10-CM Code View

HCC Buddy Code Card

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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Disorders of other endocrine glands (E20-E35)

E24.8

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other Cushing's syndrome

Cushing's syndrome caused by other specified sources not covered by the more specific Cushing's syndrome codes.

Buddy the Bee presenting code insight

Buddy Insight

Other Cushing syndrome captures specified causes of cortisol excess that do not fit the standard categories of pituitary-dependent, drug-induced, ectopic, or alcohol-related Cushing syndrome.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

HCC 23

RAF 0.194

ACA/HHS

0

0

RAF 0

ESRD/PACE

HCC 23

RAF 0.0

RXHCC

HCC 43

RAF 0.0

Code Trumping

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Code Book Path

Official
E24Cushing's syndrome
E24.8Other Cushing's syndrome

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E24.8 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E24.8 in this effective period.

Related Child Codes

Official
E24.0Pituitary-dependent Cushing's disease
E24.1Nelson's syndrome
E24.2Drug-induced Cushing's syndrome
E24.3Ectopic ACTH syndrome
E24.4Alcohol-induced pseudo-Cushing's syndrome

Includes

Official

ICD-10-CM does not list Includes notes for E24.8 in this effective period.

Excludes 1

Official
  • congenital adrenal hyperplasia (E25.0)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E24.8 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E24.8 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E24.8 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Document the specific identified etiology of the Cushing syndrome, cortisol and adrenocorticotropic hormone levels, imaging findings, clinical manifestations, and the reasoning for classifying under this residual category rather than a more specific code.

MEAT Support

HCC Buddy guidance
Document the specific identified etiology of the Cushing syndrome, cortisol and adrenocorticotropic hormone levels, imaging findings, clinical manifestations, and the reasoning for classifying under this residual category rather than a more specific code.

Audit Caution

HCC Buddy guidance
This code should only be used when the specific cause is identified but does not match codes E24.0 through E24.
If the cause is unknown, use E24.9 instead. Document the specific etiology clearly to support medical necessity for this residual code.

Common Mistakes

HCC Buddy guidance
E24.0 (pituitary-dependent Cushing disease), E24.2 (drug-induced), E24.3 (ectopic adrenocorticotropic hormone), E24.9 (unspecified Cushing syndrome), E27.0 (other adrenocortical overactivity).

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is E24.8 an HCC code?

Yes. E24.8 maps to Other Significant Endocrine and Metabolic Disorders under the V24 model but is not retained in V28.

HCC Category Mapping

V24HCC 23, Other Significant Endocrine and Metabolic Disorders
0.194
ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders
0.000
RxHCCHCC 43, Other Significant Endocrine and Metabolic Disorders
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work E24.8 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for E24.8

For E24.8to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E24.8 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E24.8 is the ICD-10-CM diagnosis code for other cushing's syndrome. Cushing's syndrome caused by other specified sources not covered by the more specific Cushing's syndrome codes. E24.8 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering disorders of other endocrine glands (e20-e35).

Under the older CMS-HCC V24 model, E24.8 maps to Other Significant Endocrine and Metabolic Disorders (HCC 23) with a community, non-dual, aged base RAF weight of 0.194. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Use this code when the cause is identified but does not fit into categories 0-4 or 9. Because E24.8 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E24.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use this code when the cause is identified but does not fit into categories 0-4 or 9
  • Document the specific etiology clearly in the medical record

Clinical Significance

Other Cushing syndrome captures specified causes of cortisol excess that do not fit the standard categories of pituitary-dependent, drug-induced, ectopic, or alcohol-related Cushing syndrome. This may include rare causes such as adrenocorticotropic hormone-independent macronodular adrenal hyperplasia, primary pigmented nodular adrenocortical disease, or McCune-Albright syndrome.

Documentation Requirements

  • Document the specific identified etiology of the Cushing syndrome, cortisol and adrenocorticotropic hormone levels, imaging findings, clinical manifestations, and the reasoning for classifying under this residual category rather than a more specific code.

Commonly Confused Codes

  • E24.0 (pituitary-dependent Cushing disease), E24.2 (drug-induced), E24.3 (ectopic adrenocorticotropic hormone), E24.9 (unspecified Cushing syndrome), E27.0 (other adrenocortical overactivity).

Child Codes

Code Hierarchy

Because E24.8 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

Work E24.8 in HCC Buddy

Open E24.8 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 14 days to try everything.