FY2027 ICD-10-CM reference
E11.21: Type 2 diabetes mellitus with diabetic nephropathy
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Type 2 diabetes mellitus with diabetic nephropathy. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: E00-E89 (chapter, inherited).
Excludes1
transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Source: E00-E89 (chapter, inherited).
Includes
diabetes (mellitus) due to insulin secretory defect
Source: E11 (category, inherited).
Includes
diabetes NOS
Source: E11 (category, inherited).
Includes
insulin resistant diabetes (mellitus)
Source: E11 (category, inherited).
Instructional note
code to identify control using:
Source: E11 (category, inherited).
Instructional note
injectable non-insulin antidiabetic drugs (Z79.85)
Source: E11 (category, inherited).
Instructional note
insulin (Z79.4)
Source: E11 (category, inherited).
Instructional note
oral antidiabetic drugs (Z79.84)
Source: E11 (category, inherited).
Instructional note
oral hypoglycemic drugs (Z79.84)
Source: E11 (category, inherited).
Excludes1
diabetes mellitus due to underlying condition (E08.-)
Source: E11 (category, inherited).
Excludes1
drug or chemical induced diabetes mellitus (E09.-)
Source: E11 (category, inherited).
Excludes1
gestational diabetes (O24.4-)
Source: E11 (category, inherited).
Excludes1
neonatal diabetes mellitus (P70.2)
Source: E11 (category, inherited).
Excludes1
postpancreatectomy diabetes mellitus (E13.-)
Source: E11 (category, inherited).
Excludes1
postprocedural diabetes mellitus (E13.-)
Source: E11 (category, inherited).
Excludes1
secondary diabetes mellitus NEC (E13.-)
Source: E11 (category, inherited).
Excludes1
type 1 diabetes mellitus (E10.-)
Source: E11 (category, inherited).
Instructional note
Type 2 diabetes mellitus with intercapillary glomerulosclerosis
Source: E11.21 (self, direct).
Instructional note
Type 2 diabetes mellitus with intracapillary glomerulonephrosis
Source: E11.21 (self, direct).
Instructional note
Type 2 diabetes mellitus with Kimmelstiel-Wilson disease
Source: E11.21 (self, direct).
Compare the FY2027 additions, removals and billable-status changes
What does E11.21 mean in FY2027?
The official ICD-10-CM descriptor is Type 2 diabetes mellitus with diabetic nephropathy. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is E11.21 billable in FY2027?
The FY2027 order file marks E11.21 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does E11.21 map to an HCC?
In the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service), E11.21 maps to CMS-HCC V28 HCC 37 (Diabetes with Chronic Complications). For 2027 dates of service, CMS has not yet published the payment year 2028 mappings. ESRD, RxHCC, PACE and HHS-HCC mappings are still pending verification for FY2027.
Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.
Review the FY2026 April edition