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E09.621 ICD-10-CM Code: Drug or chemical induced diabetes mellitus with foot ulcer

E09.621 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupE09.621

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Diabetes mellitus (E08-E13)

E09.621

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Drug or chemical induced diabetes mellitus with foot ulcer

This code describes diabetes that developed as a side effect of taking certain medications or being exposed to harmful chemicals, and the patient has developed an ulcer (open sore) on their foot. This is a serious complication that requires careful wound care and management.

Buddy the Bee presenting code insight

Buddy Insight

Drug or chemical induced diabetes mellitus with foot ulcer is a serious complication combining impaired wound healing from diabetes with the biomechanical stresses on the foot.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 020

Code-level coefficient reference

ESRD/PACE

HCC 18

Code-level coefficient reference

+ HCC 161

RXHCC

HCC 30

Code-level coefficient reference

+ HCC 311

Inclusion Terms

Official

No inclusion terms are included in this display for E09.621. Check the code and parent instructions in the Code Book.

Excludes 2

Official

No Excludes 2 notes are included in this display for E09.621. Check the code and parent instructions in the Code Book.

Includes

Official

No Includes notes are included in this display for E09.621. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89, E09
  • diabetes mellitus due to underlying condition (E08.-)Inherited from E00-E89, E09
  • gestational diabetes (O24.4-)Inherited from E00-E89, E09
  • neonatal diabetes mellitus (P70.2)Inherited from E00-E89, E09
  • postpancreatectomy diabetes mellitus (E13.-)Inherited from E00-E89, E09
  • postprocedural diabetes mellitus (E13.-)Inherited from E00-E89, E09
  • secondary diabetes mellitus NEC (E13.-)Inherited from E00-E89, E09
  • type 1 diabetes mellitus (E10.-)Inherited from E00-E89, E09
  • type 2 diabetes mellitus (E11.-)Inherited from E00-E89, E09

Code First

Official
  • poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)Inherited from E09

Use Additional

Official
  • code to identify site of ulcer (L97.4-, L97.5-)
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)Inherited from E09
  • code to identify control using:Inherited from E09
  • injectable non-insulin antidiabetic drugs (Z79.85)Inherited from E09
  • insulin (Z79.4)Inherited from E09
  • oral antidiabetic drugs (Z79.84)Inherited from E09
  • oral hypoglycemic drugs (Z79.84)Inherited from E09

Code Also

Official

No Code Also instructions are included in this display for E09.621. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
The causative drug or chemical must be identified.
The foot ulcer must be documented with its exact anatomical location, size, depth, and Wagner or University of Texas classification.
An additional code from L97 (non-pressure chronic ulcer of lower limb) specifying site and severity is required.
Vascular status and presence or absence of infection must be assessed and documented.

MEAT Support

HCC Buddy guidance
The causative drug or chemical must be identified.
The foot ulcer must be documented with its exact anatomical location, size, depth, and Wagner or University of Texas classification.
An additional code from L97 (non-pressure chronic ulcer of lower limb) specifying site and severity is required.
Vascular status and presence or absence of infection must be assessed and documented.

Audit Caution

HCC Buddy guidance
The L97 additional code specifying ulcer laterality, location, and severity is frequently omitted.
Wound infection requires separate coding (L08 series).
Ensure the foot ulcer is documented as related to diabetes, not trauma or pressure.
This code has no HCC mapping, so capturing all coexisting complications is essential.

Common Mistakes

HCC Buddy guidance
E09.622 (other skin ulcer) applies to ulcers outside the foot.
E09.620 (dermatitis) is an inflammatory condition without ulceration.
E09.52 (peripheral angiopathy with gangrene) represents more advanced tissue death.
L97 codes specify ulcer location and severity and should be coded in addition to E09.621.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E09.621 an HCC code?

E09.621 is not in the CMS-HCC V28 or V24 community payment model. E09.621 has a separate mapping under the CMS-HCC ESRD model (HCC 18 (Diabetes with Chronic Complications) and HCC 161 (Chronic Ulcer of Skin/Except Pressure)) and the Part D RxHCC model (HCC 30 (Diabetes with Complications) and HCC 311 (Chronic Ulcer of Skin, Except Pressure)); the applicable result needs member context. E09.621 also appears in the HHS-HCC commercial risk model (HCC 020 (HHS-HCC 020 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.

Code
E09.621
Description
Drug or chemical induced diabetes mellitus with foot ulcer
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
Yes
Payment year
2026

HCC Category Mapping

ESRDHCC 18, Diabetes with Chronic Complications
Not separately weighted
+ HCC 161, Chronic Ulcer of Skin/Except PressureNot separately weighted
RxHCCHCC 30, Diabetes with Complications
Not separately weighted
+ HCC 311, Chronic Ulcer of Skin, Except PressureNot separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work E09.621 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for E09.621

For E09.621, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

E09.621 is the ICD-10-CM diagnosis code for drug or chemical induced diabetes mellitus with foot ulcer. This code describes diabetes that developed as a side effect of taking certain medications or being exposed to harmful chemicals, and the patient has developed an ulcer (open sore) on their foot. This is a serious complication that requires careful wound care and management. E09.621 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering diabetes mellitus (e08-e13).

E09.621 has no mapping under the CMS-HCC V28 or V24 community payment models. E09.621 has a separate mapping under the CMS-HCC ESRD model (HCC 18 (Diabetes with Chronic Complications) and HCC 161 (Chronic Ulcer of Skin/Except Pressure)) and the Part D RxHCC model (HCC 30 (Diabetes with Complications) and HCC 311 (Chronic Ulcer of Skin, Except Pressure)); the applicable result needs member context. E09.621 also appears in the HHS-HCC commercial risk model (HCC 020 (HHS-HCC 020 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

Always identify and document the specific drug or chemical that caused the diabetes, as this information supports medical necessity and helps with causality documentation.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E09.621 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Always identify and document the specific drug or chemical that caused the diabetes, as this information supports medical necessity and helps with causality documentation
  • Ensure the foot ulcer is documented with its location and severity (stage), as this may require additional codes for the ulcer itself (L97 series) depending on your coding guidelines and payer requirements

Clinical Significance

Drug or chemical induced diabetes mellitus with foot ulcer is a serious complication combining impaired wound healing from diabetes with the biomechanical stresses on the foot. Diabetic foot ulcers are a leading cause of nontraumatic lower extremity amputation and represent a major source of morbidity, prolonged hospitalization, and healthcare expenditure. The presence of a foot ulcer in drug-induced diabetes signals the need for multidisciplinary care including vascular assessment, wound management, and offloading strategies.

Documentation Requirements

  • The causative drug or chemical must be identified.
  • The foot ulcer must be documented with its exact anatomical location, size, depth, and Wagner or University of Texas classification.
  • An additional code from L97 (non-pressure chronic ulcer of lower limb) specifying site and severity is required.
  • Vascular status and presence or absence of infection must be assessed and documented.

Use Additional Code

Commonly Confused Codes

  • E09.622 (other skin ulcer) applies to ulcers outside the foot.
  • E09.620 (dermatitis) is an inflammatory condition without ulceration.
  • E09.52 (peripheral angiopathy with gangrene) represents more advanced tissue death.
  • L97 codes specify ulcer location and severity and should be coded in addition to E09.621.

Child Codes

Code Hierarchy

Work E09.621 in HCC Buddy

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