D22.121 ICD-10-CM Code: Melanocytic nevi of left upper eyelid, including canthus
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FY 2026 Apr update / Neoplasms (C00-D49) / Benign neoplasms, except benign neuroendocrine tumors (D10-D36)
D22.121
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceMelanocytic nevi of left upper eyelid, including canthus
This code describes a benign mole (melanocytic nevus) located on the left upper eyelid or the corner of the eye. These are common, non-cancerous skin growths that are typically brown or tan in color.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
N/A—
Not mapped
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for D22.121 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for D22.121 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for D22.121 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for D22.121 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for D22.121 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for D22.121 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for D22.121 in this effective period.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is D22.121 an HCC code?
No. D22.121 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
- Code
- D22.121
- Description
- Melanocytic nevi of left upper eyelid, including canthus
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
D22.121 is the ICD-10-CM diagnosis code for melanocytic nevi of left upper eyelid, including canthus. This code describes a benign mole (melanocytic nevus) located on the left upper eyelid or the corner of the eye. These are common, non-cancerous skin growths that are typically brown or tan in color. D22.121 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering benign neoplasms, except benign neuroendocrine tumors (d10-d36).
D22.121 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Verify laterality (left vs. right) and anatomical location (upper vs. lower eyelid) in the documentation before assigning this code.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D22.121 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Verify laterality (left vs. right) and anatomical location (upper vs. lower eyelid) in the documentation before assigning this code
- •This code is for benign nevi only; if there is any concern for malignancy or if the lesion is documented as melanoma, use a different code from the C8x series instead

