C83.10 ICD-10-CM Code: Mantle cell lymphoma, unspecified site
C83.10 maps to CMS-HCC V28 20. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · free HCC coding tools
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FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
C83.10
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceMantle cell lymphoma, unspecified site
Mantle cell lymphoma is a type of cancer that starts in the lymph nodes and can spread to other parts of the body. This code is used when the specific location of the cancer is not documented or specified.
Buddy Insight
Mantle cell lymphoma is an aggressive B-cell non-Hodgkin lymphoma arising from the mantle zone of lymph node germinal centers.
CMS-HCC V28
MappedHCC 20
Coefficient HCC 20: 1.136 (Community Non-Dual Aged (CNA))
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
MappedHCC 010
Code-level coefficient reference
ESRD/PACE
MappedHCC 10
Code-level coefficient reference
RXHCC
MappedHCC 19
Code-level coefficient reference
Code Book Path
Inclusion Terms
Official- Centrocytic lymphomaInherited from C83.1
- Malignant lymphomatous polyposisInherited from C83.1
Excludes 2
Official- Kaposi's sarcoma of lymph nodes (C46.3)Inherited from C81-C96
- secondary and unspecified neoplasm of lymph nodes (C77.-)Inherited from C81-C96
- secondary neoplasm of bone marrow (C79.52)Inherited from C81-C96
- secondary neoplasm of spleen (C78.89)Inherited from C81-C96
Related Codes
Includes
OfficialNo Includes notes are included in this display for C83.10. Check the code and parent instructions in the Code Book.
Excludes 1
Official- personal history of non-Hodgkin lymphoma (Z85.72)Inherited from C83
Code First
OfficialNo Code First sequencing instructions are included in this display for C83.10. Check the code and parent instructions in the Code Book.
Use Additional
OfficialNo Use Additional Code instructions are included in this display for C83.10. Check the code and parent instructions in the Code Book.
Code Also
OfficialNo Code Also instructions are included in this display for C83.10. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is C83.10 an HCC code?
Yes. C83.10 (Mantle cell lymphoma, unspecified site) maps to HCC 20, Lung and Other Severe Cancers under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 1.136. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.
Coder answer: C83.10 is billable and maps to V28 HCC 20, Lung and Other Severe Cancers. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.
- Code
- C83.10
- Description
- Mantle cell lymphoma, unspecified site
- HCC (V28)
- HCC 20 — Lung and Other Severe Cancers
- RAF reference coefficient
- 1.136
- Billable
- Yes
- Payment year
- 2026
HCC Category Mapping
These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.
Work C83.10 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →
MEAT review for C83.10
For C83.10, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Coder workflow notes
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What This Code Means
C83.10 is the ICD-10-CM diagnosis code for mantle cell lymphoma, unspecified site. Mantle cell lymphoma is a type of cancer that starts in the lymph nodes and can spread to other parts of the body. This code is used when the specific location of the cancer is not documented or specified. C83.10 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).
Under the CMS-HCC V28 risk adjustment model, C83.10 maps to Lung and Other Severe Cancers (HCC 20) with a source-labeled community, non-dual, aged reference coefficient of 1.136. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.
If the site of the mantle cell lymphoma is documented (such as lymph nodes of head, neck, chest, abdomen, etc.), use a more specific code from the C83.1- subcategory rather than the unspecified code. For C83.10, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C83.10 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •If the site of the mantle cell lymphoma is documented (such as lymph nodes of head, neck, chest, abdomen, etc.), use a more specific code from the C83.1- subcategory rather than the unspecified code
- •Mantle cell lymphoma is typically an aggressive form of non-Hodgkin lymphoma; ensure documentation supports the diagnosis and verify staging information is captured separately if available
Clinical Significance
Mantle cell lymphoma is an aggressive B-cell non-Hodgkin lymphoma arising from the mantle zone of lymph node germinal centers. It accounts for approximately 5-7% of all non-Hodgkin lymphomas and typically presents at advanced stages. The unspecified site code should be used only when documentation does not identify the specific lymph node region involved.
Documentation Requirements
- ✓Pathology confirmation with immunohistochemistry (cyclin D1 positive, CD5+, CD20+)
- ✓FISH or PCR for t(11;14) translocation confirmation
- ✓Ki-67 proliferation index (blastoid variant has worse prognosis)
- ✓Ann Arbor staging with bulk disease assessment
- ✓MIPI (Mantle Cell Lymphoma International Prognostic Index) score documentation
Commonly Confused Codes
- •C83.30: Diffuse large B-cell lymphoma, unspecified; different histological subtype requiring pathology differentiation
- •C85.10: Unspecified non-Hodgkin lymphoma; always use specific subtype when pathology is available
- •C91.10: Chronic lymphocytic leukemia; CLL/SLL shares CD5 positivity but is cyclin D1 negative
- •C83.00: Small cell B-cell lymphoma; can overlap morphologically but mantle cell has characteristic cyclin D1 expression