C82.68
BillableCutaneous follicle center lymphoma, lymph nodes of multiple sites
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of lymphoma that starts in the skin and affects lymph nodes in multiple locations throughout the body.
Coding Tips
- •This code indicates involvement of lymph nodes at multiple anatomical sites; document which specific sites are affected
- •Confirm cutaneous origin is documented before coding as cutaneous follicle center lymphoma
Clinical Significance
Cutaneous follicle center lymphoma involving lymph nodes at multiple sites indicates widespread nodal disease in the context of a primary cutaneous lymphoma. Multi-site nodal involvement is uncommon for primary cutaneous follicle center lymphoma and should trigger careful reassessment of whether the disease is truly primary cutaneous or represents systemic follicular lymphoma with secondary skin involvement. The distinction affects treatment approach and prognosis significantly.
Documentation Requirements
- ✓Skin biopsy confirming cutaneous follicle center lymphoma
- ✓Imaging documenting lymph node involvement at two or more distinct anatomic regions
- ✓Documentation of all involved nodal regions
- ✓Clinical discussion addressing whether multi-site nodal disease is consistent with primary cutaneous classification
- ✓Complete staging evaluation including bone marrow assessment if indicated
Commonly Confused Codes
C82.58 — Diffuse follicle center lymphoma, lymph nodes of multiple sites: Systemic type without cutaneous primaryC82.88 — Other types of follicular lymphoma, lymph nodes of multiple sites: Different follicular subtypeC82.69 — Cutaneous follicle center lymphoma, extranodal and solid organ sites: Use when extranodal organs are involved rather than lymph nodes