C81.99
BillableHodgkin lymphoma, unspecified, extranodal and solid organ sites
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of blood cancer called Hodgkin lymphoma that has spread to organs or tissues outside the lymph node system.
Coding Tips
- •This code indicates extranodal involvement; document which specific organs or tissues are affected
- •Extranodal sites may include liver, bone, lungs, or other solid organs
Clinical Significance
Hodgkin lymphoma of unspecified type with extranodal and solid organ involvement represents stage IV disease without histologic subtype classification. Organ involvement (liver, lung, bone, bone marrow) indicates the most advanced stage and drives the most intensive treatment protocols. Determining the specific subtype is important for optimal treatment selection but should not delay initiation of therapy.
Documentation Requirements
- ✓Confirmed Hodgkin lymphoma diagnosis with organ involvement
- ✓Documentation of specific extranodal organ(s) affected
- ✓Imaging or biopsy confirmation of extranodal spread
- ✓Stage IV designation
- ✓Active treatment plan and encounter assessment
Commonly Confused Codes
C81.97 — Hodgkin lymphoma, unspecified, spleen: use C81.97 specifically for splenic involvement; C81.99 is for other extranodal sitesC81.98 — Hodgkin lymphoma, unspecified, multiple node sites: C81.98 is for multi-site nodal disease; C81.99 is for organ involvementC78-C79 — Secondary malignant neoplasm codes: lymphoma organ involvement is coded as primary lymphoma, never as secondary neoplasm