C81.45
BillableLymphocyte-rich Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of Hodgkin lymphoma with mostly lymphocytes that has spread to lymph nodes in the groin and lower legs.
Coding Tips
- •Document whether involvement is unilateral or bilateral for complete clinical picture
- •This code includes both inguinal and lower limb lymph node involvement
Clinical Significance
Lymphocyte-rich Hodgkin lymphoma involving inguinal and lower limb lymph nodes is an uncommon presentation pattern for this favorable-prognosis subtype. Inguinal nodal disease may initially suggest other etiologies including infection, dermatologic conditions, or other malignancies. Once confirmed, the lymphocyte-rich histology carries good response rates to standard treatment protocols.
Documentation Requirements
- ✓Pathology confirming lymphocyte-rich Hodgkin lymphoma from inguinal or lower limb biopsy
- ✓Physical exam or imaging documenting inguinal or lower limb lymph node involvement
- ✓Unilateral versus bilateral involvement documentation
- ✓Staging workup to evaluate for additional sites
- ✓Provider assessment and management plan
Commonly Confused Codes
C81.46 — Lymphocyte-rich Hodgkin lymphoma, intrapelvic: inguinal nodes are superficial groin nodes; intrapelvic nodes are deep within the pelvic cavityC81.25 — Mixed cellularity Hodgkin lymphoma, inguinal/lower limb: same location, different subtypeR59.1 — Generalized enlarged lymph nodes: use only before malignancy is confirmed