C81.40
BillableLymphocyte-rich Hodgkin lymphoma, unspecified site
Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)
Is C81.40 an HCC code?
Yes. C81.40 maps to Breast, Prostate, Colorectal and Other Cancers and Tumors under the CMS-HCC V28 risk adjustment model (and Lymphoma and Other Cancers under V24).
HCC Category Mapping
RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
MEAT Criteria for C81.40
For C81.40 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed C81.40 during that encounter — not just copy-forwarded from a problem list.
What This Code Means
C81.40 is the ICD-10-CM diagnosis code for lymphocyte-rich hodgkin lymphoma, unspecified site. A rare type of Hodgkin lymphoma (lymphocyte-rich variant) with an unspecified location of involvement. C81.40 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).
Under the CMS-HCC V28 risk adjustment model, C81.40 maps to Breast, Prostate, Colorectal and Other Cancers and Tumors (HCC 21) with a community, non-dual, aged base RAF weight of 0.545. Under the older CMS-HCC V24 model, C81.40 maps to Lymphoma and Other Cancers (HCC 10) with a community, non-dual, aged base RAF weight of 0.675. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
Use this code only when the specific site of lymphoma involvement is not documented. Because C81.40 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C81.40 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Use this code only when the specific site of lymphoma involvement is not documented
- •Query the provider if site information is available to assign a more specific code
Clinical Significance
Lymphocyte-rich Hodgkin lymphoma is a relatively uncommon subtype of classical Hodgkin lymphoma with the most favorable prognosis among all Hodgkin subtypes, often presenting at an early stage. The unspecified site designation means the anatomic location was not documented. Despite its indolent behavior, these patients require ongoing monitoring and treatment, and the code is important for risk adjustment capture.
Documentation Requirements
- ✓Pathology confirming lymphocyte-rich classical Hodgkin lymphoma (distinct from nodular lymphocyte predominant Hodgkin lymphoma, which is classified separately)
- ✓Query provider for anatomic site when available to use a more specific code
- ✓Ann Arbor staging documentation
- ✓Treatment status: active therapy, watch-and-wait, or surveillance
- ✓Provider assessment during the encounter
Commonly Confused Codes
- •C81.30 — Lymphocyte depleted Hodgkin lymphoma, unspecified: opposite histologic pattern with vastly different prognosis; pathology distinction is critical
- •C81.00 — Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site: this is a SEPARATE entity from lymphocyte-rich classical Hodgkin lymphoma with different biology and treatment
- •C81.90 — Hodgkin lymphoma, unspecified type: use C81.40 when the subtype is confirmed as lymphocyte-rich even if the site is not documented