F33.42 ICD-10-CM Code: Major depressive disorder, recurrent, in full remission
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FY 2026 Apr update / Mental, Behavioral and Neurodevelopmental disorders (F01-F99) / Mood [affective] disorders (F30-F39)
F33.42
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceMajor depressive disorder, recurrent, in full remission
A condition where a person has experienced multiple episodes of major depression and is currently in full remission, meaning depression symptoms have completely resolved.
Buddy Insight
Major depressive disorder, recurrent, in full remission indicates complete resolution of depressive symptoms in a patient with a history of multiple major depressive episodes.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
MappedHCC 59
RAF 0.309
ACA/HHS
00
RAF 0
ESRD/PACE
MappedHCC 59
RAF 0.0
RXHCC
MappedHCC 132
RAF 0.0
Code Trumping
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Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for F33.42 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for F33.42 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for F33.42 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for F33.42 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for F33.42 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for F33.42 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for F33.42 in this effective period.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is F33.42 an HCC code?
Yes. F33.42 maps to Major Depressive, Bipolar, and Paranoid Disorders under the V24 model but is not retained in V28.
HCC Category Mapping
RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
MEAT Criteria for F33.42
For F33.42to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed F33.42 during that encounter, not just copy-forwarded from a problem list.
What This Code Means
F33.42 is the ICD-10-CM diagnosis code for major depressive disorder, recurrent, in full remission. A condition where a person has experienced multiple episodes of major depression and is currently in full remission, meaning depression symptoms have completely resolved. F33.42 sits in the ICD-10-CM chapter for mental, behavioral and neurodevelopmental disorders (f01-f99), within the section covering mood [affective] disorders (f30-f39).
Under the older CMS-HCC V24 model, F33.42 maps to Major Depressive, Bipolar, and Paranoid Disorders (HCC 59) with a community, non-dual, aged base RAF weight of 0.309. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
Only use this code when documentation explicitly states the patient is in full remission with no current depressive symptoms. Because F33.42 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for F33.42 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Only use this code when documentation explicitly states the patient is in full remission with no current depressive symptoms
- •This indicates a better prognosis than partial remission codes
Clinical Significance
Major depressive disorder, recurrent, in full remission indicates complete resolution of depressive symptoms in a patient with a history of multiple major depressive episodes. Despite full remission, the recurrent history warrants continued maintenance treatment, as relapse rates are high (over 50% after two episodes). This code supports ongoing psychiatric management and medication continuation.
Documentation Requirements
- ✓Documented history of recurrent major depressive disorder
- ✓Full remission with complete absence of depressive symptoms
- ✓Maintenance medication regimen (typically indefinite for recurrent MDD)
- ✓Follow-up monitoring plan for relapse prevention
- ✓Provider statement confirming full remission
Commonly Confused Codes
- •F33.41: Major depressive disorder, recurrent, partial remission: Residual symptoms still present
- •F32.5: Major depressive disorder, single episode, full remission: Only one prior episode
- •Z86.59: Personal history of mental and behavioral disorders: Only if truly no longer managed
- •F33.40: Major depressive disorder, recurrent, remission unspecified: Less specific