What is ICD-10 code E70.338?

E70.338 is the ICD-10-CM diagnosis code for Other albinism with hematologic abnormality. A rare condition where abnormal skin and hair pigmentation (albinism) occurs alongside blood cell disorders, excluding Chediak-Higashi syndrome. It belongs to the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89). E70.338 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. E70.338 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. E70.338 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. E70.338 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Which HCC does E70.338 map to under V28?

E70.338 has no payable CMS-HCC V28 mapping in the final FY2026 CMS file.

What RAF reference is published for E70.338?

E70.338 has no V28 reference coefficient because the final FY2026 source verifies no payable V28 mapping.

What is the V28 vs V24 difference for E70.338?

E70.338 has verified no payable V28 mapping in the final FY2026 source. Select a historical effective period before making any V24 comparison.

What documentation supports E70.338?

Use this code only when albinism with hematologic abnormality is documented but is not Chediak-Higashi syndrome Ensure documentation specifies the type of hematologic abnormality present to support medical necessity E70.338 is not a CMS-HCC V28 payment code in the verified current source, so MEAT is not the payment hook. Documentation still has to support the diagnosis if you report it.

2026 ICD-10-CM E70.338: Other albinism with hematologic

E70.338 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software

ICD-10-CM Code View

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Code lookupE70.338Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E70.338

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other albinism with hematologic abnormality

A rare condition where abnormal skin and hair pigmentation (albinism) occurs alongside blood cell disorders, excluding Chediak-Higashi syndrome.

Buddy Insight

CMS-HCC V28

N/A

—

Not risk-adjusted for this model/period.

Not mapped

CMS-HCC V24

Historical

Not used for standard CY2026 Medicare Advantage payment. Select a historical period to review V24.

Not used for CY2026 payment

ACA/HHS

N/A

—

Not risk-adjusted for this model/period.

Not mapped

ESRD/PACE

N/A

—

Not risk-adjusted for this model/period.

Not mapped

RXHCC

Mapped

HCC 43

Pituitary, Adrenal Gland, and...

Code-level coefficient reference

Code Book Path

Official

E70.3Albinism

E70.33Albinism with hematologic abnormality

E70.338Other albinism with hematologic abnormality

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E70.338 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E70.338 in this effective period.

Related Child Codes

Official

E70.330Chediak-Higashi syndrome

E70.331Hermansky-Pudlak syndrome

E70.339Albinism with hematologic abnormality, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for E70.338 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for E70.338 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E70.338 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E70.338 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E70.338 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance

Documentation should specify the exact condition diagnosed, supporting genetic test results, characterization of both the pigmentation defect and the hematologic abnormality (type, severity, clinical impact), and any organ complications.

The provider should clearly document why this does not qualify as Chediak-Higashi or Hermansky-Pudlak syndrome.

Treatment regimen and monitoring plan should be detailed.

MEAT Support

HCC Buddy guidance

The provider should clearly document why this does not qualify as Chediak-Higashi or Hermansky-Pudlak syndrome.

Treatment regimen and monitoring plan should be detailed.

Audit Caution

HCC Buddy guidance

Do not use this code when Chediak-Higashi or Hermansky-Pudlak syndrome has been confirmed

those have their own specific codes. Ensure both the albinism and hematologic components are documented and causally linked as part of the same genetic syndrome. Code organ-specific complications separately. Griscelli syndrome and similar rare conditions should use this code when specific codes are not available.

Common Mistakes

HCC Buddy guidance

E70.330 (Chediak-Higashi syndrome) and E70.331 (Hermansky-Pudlak syndrome) are specific named syndromes that should be used when confirmed.

E70.339 (Albinism with hematologic abnormality, unspecified) is for cases where the specific type cannot be determined.

E70.320-E70.329 (Oculocutaneous albinism) does not include hematologic components.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E70.338 an HCC code?

E70.338 is not in the CMS-HCC V28 or V24 community payment model. E70.338 has a separate mapping under the CMS-HCC ESRD model (HCC 23 (Other Significant Endocrine and Metabolic Disorders)) and the Part D RxHCC model (HCC 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders)); the applicable result needs member context. E70.338 also appears in the HHS-HCC commercial risk model (HCC 028 (HHS-HCC 028 child, RAF varies by metal level)), where the result depends on member context and is not a Medicare Advantage payment mapping.

Code: E70.338
Description: Other albinism with hematologic abnormality
HCC (V28): No CMS-HCC V28 mapping
RAF reference coefficient: —
Billable: Yes
Payment year: 2026

HCC Category Mapping

RxHCCHCC 43, Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders

Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work E70.338 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT Criteria for E70.338

For E70.338 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E70.338 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E70.338 is the ICD-10-CM diagnosis code for other albinism with hematologic abnormality. A rare condition where abnormal skin and hair pigmentation (albinism) occurs alongside blood cell disorders, excluding Chediak-Higashi syndrome. E70.338 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

E70.338 has no mapping under the CMS-HCC V28 or V24 community payment models. E70.338 has a separate mapping under the CMS-HCC ESRD model (HCC 23 (Other Significant Endocrine and Metabolic Disorders)) and the Part D RxHCC model (HCC 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders)); the applicable result needs member context. E70.338 also appears in the HHS-HCC commercial risk model (HCC 028 (HHS-HCC 028 child, RAF varies by metal level)), where the result depends on member context and is not a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

Use this code only when albinism with hematologic abnormality is documented but is not Chediak-Higashi syndrome.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E70.338 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•Use this code only when albinism with hematologic abnormality is documented but is not Chediak-Higashi syndrome
•Ensure documentation specifies the type of hematologic abnormality present to support medical necessity

Clinical Significance

Other albinism with hematologic abnormality captures rare genetic conditions combining pigmentation defects with blood cell disorders that do not meet criteria for Chediak-Higashi syndrome or Hermansky-Pudlak syndrome. These may include Griscelli syndrome or other rare melanocyte and platelet granule disorders, each carrying distinct clinical implications for infection risk, bleeding, and organ-specific complications.

Documentation Requirements

✓Documentation should specify the exact condition diagnosed, supporting genetic test results, characterization of both the pigmentation defect and the hematologic abnormality (type, severity, clinical impact), and any organ complications.
✓The provider should clearly document why this does not qualify as Chediak-Higashi or Hermansky-Pudlak syndrome.
✓Treatment regimen and monitoring plan should be detailed.

Commonly Confused Codes

•E70.330 (Chediak-Higashi syndrome) and E70.331 (Hermansky-Pudlak syndrome) are specific named syndromes that should be used when confirmed.
•E70.339 (Albinism with hematologic abnormality, unspecified) is for cases where the specific type cannot be determined.
•E70.320-E70.329 (Oculocutaneous albinism) does not include hematologic components.