What is ICD-10 code E70.310?

E70.310 is the ICD-10-CM diagnosis code for X-linked ocular albinism. A rare inherited condition affecting only the eyes where melanin production is reduced, causing vision problems and light sensitivity, inherited through the X chromosome. It belongs to the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89). E70.310 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. E70.310 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. E70.310 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. E70.310 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Which HCC does E70.310 map to under V28?

E70.310 does not map to a CMS-HCC V28 payment category. Check the current CMS-HCC V28 model file for payment year 2026 rather than an older V24 tip sheet.

What does E70.310 pay in RAF?

E70.310 has no separately stated V28 community RAF weight. If it is not a V28 payment HCC, it adds nothing to a community RAF score.

What is the V28 vs V24 difference for E70.310?

CMS phased in the V28 risk adjustment model over payment years 2024 (33%), 2025 (67%), and 2026 (100%), replacing V24. V28 consolidates HCC categories, removes some lower-acuity conditions, and recalibrates RAF weights across the entire model. E70.310 was a payment HCC under V24 (Other Significant Endocrine and Metabolic Disorders) but the V28 recalibration removed it from the risk adjustment model. Both models can still appear in legacy data and in payer-specific lookback periods.

What documentation supports E70.310?

This X-linked form primarily affects males; verify patient gender and family history in documentation Code any associated vision complications separately, such as nystagmus or reduced visual acuity Because E70.310 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score. See the MEAT criteria checklist at /meat-criteria for what Monitor, Evaluate, Assess, or Treat looks like in a note. MEAT is generic documentation evidence, not a payer-specific rule.

2026 ICD-10-CM E70.310: X-linked ocular albinism

E70.310 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools

ICD-10-CM Code View

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Code lookupE70.310Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E70.310

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

X-linked ocular albinism

A rare inherited condition affecting only the eyes where melanin production is reduced, causing vision problems and light sensitivity, inherited through the X chromosome.

Buddy Insight

X-linked ocular albinism is an inherited condition primarily affecting males, caused by mutations in the GPR143 gene on the X chromosome.

CMS-HCC V28

N/A

—

Not risk-adjusted for this model/period.

Not mapped

CMS-HCC V24

Mapped

HCC 23

Other Significant Endocrine a...

RAF 0.194

ACA/HHS

Mapped

HCC 28

HHS-HCC 28

Varies by metal level

ESRD/PACE

Mapped

HCC 23

Other Significant Endocrine a...

RAF 0.036

RXHCC

Mapped

HCC 43

Other Significant Endocrine a...

RAF 0.063

Code Book Path

Official

E70.3Albinism

E70.31Ocular albinism

E70.310X-linked ocular albinism

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E70.310 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E70.310 in this effective period.

Related Child Codes

Official

E70.311Autosomal recessive ocular albinism

E70.318Other ocular albinism

E70.319Ocular albinism, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for E70.310 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for E70.310 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E70.310 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E70.310 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E70.310 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance

Documentation should include genetic testing confirming X-linked inheritance, comprehensive ophthalmologic examination findings (visual acuity, fundoscopy showing hypopigmented retinal pigment epithelium, iris transillumination, nystagmus characterization), and family history consistent with X-linked pattern.

Note any foveal hypoplasia on optical coherence tomography.

Document that skin and hair pigmentation are relatively preserved to distinguish from oculocutaneous forms.

MEAT Support

HCC Buddy guidance

Note any foveal hypoplasia on optical coherence tomography.

Document that skin and hair pigmentation are relatively preserved to distinguish from oculocutaneous forms.

Audit Caution

HCC Buddy guidance

Verify the inheritance pattern before assigning this X-linked code, as autosomal recessive ocular albinism presents similarly.

Do not assign this code in females unless documentation specifically supports it (rare homozygous cases).

Code ocular complications (nystagmus, reduced visual acuity, strabismus) separately.

Ensure the provider distinguishes ocular albinism from early-onset or mild oculocutaneous albinism.

Common Mistakes

HCC Buddy guidance

E70.311 (Autosomal recessive ocular albinism) has a different inheritance pattern and affects both sexes equally.

E70.319 (Ocular albinism, unspecified) should not be used when X-linked inheritance is confirmed.

E70.320-E70.329 (Oculocutaneous albinism) involves skin pigmentation changes.

H55.0x (Nystagmus) and H53.x (Visual disturbances) may be coded additionally for specific ocular manifestations.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E70.310 an HCC code?

Yes. E70.310 maps to Other Significant Endocrine and Metabolic Disorders under the V24 model but is not retained in V28.

Code: E70.310
Description: X-linked ocular albinism
HCC (V28): No CMS-HCC V28 mapping
RAF: —
Billable: Yes
Payment year: 2026

HCC Category Mapping

V24HCC 23, Other Significant Endocrine and Metabolic Disorders

0.194

ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders

0.036

RxHCCHCC 43, Other Significant Endocrine and Metabolic Disorders

0.063

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work E70.310 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for E70.310

For E70.310 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E70.310 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E70.310 is the ICD-10-CM diagnosis code for x-linked ocular albinism. A rare inherited condition affecting only the eyes where melanin production is reduced, causing vision problems and light sensitivity, inherited through the X chromosome. E70.310 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

Under the older CMS-HCC V24 model, E70.310 maps to Other Significant Endocrine and Metabolic Disorders (HCC 23) with a community, non-dual, aged base RAF weight of 0.194. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This X-linked form primarily affects males; verify patient gender and family history in documentation. Because E70.310 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E70.310 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•This X-linked form primarily affects males; verify patient gender and family history in documentation
•Code any associated vision complications separately, such as nystagmus or reduced visual acuity

Clinical Significance

X-linked ocular albinism is an inherited condition primarily affecting males, caused by mutations in the GPR143 gene on the X chromosome. It results in reduced melanin in the retinal pigment epithelium and iris, causing decreased visual acuity, nystagmus, strabismus, and photophobia while skin and hair pigmentation remain relatively normal. Female carriers may show mosaic fundus changes on ophthalmologic examination.

Documentation Requirements

✓Documentation should include genetic testing confirming X-linked inheritance, comprehensive ophthalmologic examination findings (visual acuity, fundoscopy showing hypopigmented retinal pigment epithelium, iris transillumination, nystagmus characterization), and family history consistent with X-linked pattern.
✓Note any foveal hypoplasia on optical coherence tomography.
✓Document that skin and hair pigmentation are relatively preserved to distinguish from oculocutaneous forms.

Commonly Confused Codes

•E70.311 (Autosomal recessive ocular albinism) has a different inheritance pattern and affects both sexes equally.
•E70.319 (Ocular albinism, unspecified) should not be used when X-linked inheritance is confirmed.
•E70.320-E70.329 (Oculocutaneous albinism) involves skin pigmentation changes.
•H55.0x (Nystagmus) and H53.x (Visual disturbances) may be coded additionally for specific ocular manifestations.