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E31.2 ICD-10-CM Code: Multiple endocrine neoplasia [MEN] syndromes

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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Disorders of other endocrine glands (E20-E35)

E31.2

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Multiple endocrine neoplasia [MEN] syndromes

Multiple endocrine neoplasia [MEN] syndromes

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
E31Polyglandular dysfunction
E31.2Multiple endocrine neoplasia [MEN] syndromes

Inclusion Terms

Official
  • Multiple endocrine adenomatosis

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E31.2 in this effective period.

Related Child Codes

Official
E31.20Multiple endocrine neoplasia [MEN] syndrome, unspecified
E31.21Multiple endocrine neoplasia [MEN] type I
E31.22Multiple endocrine neoplasia [MEN] type IIA
E31.23Multiple endocrine neoplasia [MEN] type IIB

Includes

Official

ICD-10-CM does not list Includes notes for E31.2 in this effective period.

Excludes 1

Official
  • ataxia telangiectasia [Louis-Bar] (G11.3)
  • dystrophia myotonica [Steinert] (G71.11)
  • pseudohypoparathyroidism (E20.1)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E31.2 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E31.2 in this effective period.

Code Also

Official
  • any associated malignancies and other conditions associated with the syndromes

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

What This Code Means

E31.2 is the ICD-10-CM diagnosis code for multiple endocrine neoplasia [men] syndromes. E31.2 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering disorders of other endocrine glands (e20-e35).

Header codes like E31.2 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at E31.2's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E31.2 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Code Also

  • any associated malignancies and other conditions associated with the syndromes

Child Codes

Code Hierarchy

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