E08.641 ICD-10-CM Code: Diabetes mellitus due to underlying condition with hypoglycemia with coma
E08.641 maps to CMS-HCC V28 36 (RAF 0.166). Documentation must support MEAT. MEAT criteria · RAF calculator · free HCC coding tools
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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Diabetes mellitus (E08-E13)
E08.641
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceDiabetes mellitus due to underlying condition with hypoglycemia with coma
Diabetes caused by another medical condition resulting in dangerously low blood sugar levels severe enough to cause loss of consciousness.
Buddy Insight
Diabetes mellitus due to an underlying condition with hypoglycemia with coma represents a severe acute complication where hypoglycemia from insulin or oral hypoglycemic therapy has progressed to loss of consciousness.
CMS-HCC V28
MappedHCC 36
RAF 0.166
CMS-HCC V24
MappedHCC 17
RAF 0.302
ACA/HHS
MappedHCC 19
Varies by metal level
ESRD/PACE
MappedHCC 17
RAF 0.084
RXHCC
MappedHCC 30
RAF 0.495
Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for E08.641 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for E08.641 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for E08.641 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for E08.641 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for E08.641 in this effective period.
Use Additional
Official- code for hypoglycemia level, if applicable (E16.A-)
Code Also
OfficialICD-10-CM does not list Code Also instructions for E08.641 in this effective period.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is E08.641 an HCC code?
Yes. E08.641 (Diabetes mellitus due to underlying condition with hypoglycemia with coma) maps to Diabetes with Severe Acute Complications under the CMS-HCC V28 risk adjustment model (and Diabetes with Acute Complications under V24), with a community non-dual aged RAF of 0.166. It is billable for payment year 2026.
Coder answer: E08.641 is billable and maps to V28 HCC 36, Diabetes with Severe Acute Complications. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.
- Code
- E08.641
- Description
- Diabetes mellitus due to underlying condition with hypoglycemia with coma
- HCC (V28)
- HCC 36 — Diabetes with Severe Acute Complications
- RAF
- 0.166
- Billable
- Yes
- Payment year
- 2026
HCC Category Mapping
Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
Work E08.641 in the Code Book — tabular path, V28 RAF, and MEAT checklist →
MEAT Criteria for E08.641
For E08.641 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E08.641 during that encounter, not just copy-forwarded from a problem list.
Coder workflow notes
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What This Code Means
E08.641 is the ICD-10-CM diagnosis code for diabetes mellitus due to underlying condition with hypoglycemia with coma. Diabetes caused by another medical condition resulting in dangerously low blood sugar levels severe enough to cause loss of consciousness. E08.641 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering diabetes mellitus (e08-e13).
Under the CMS-HCC V28 risk adjustment model, E08.641 maps to Diabetes with Severe Acute Complications (HCC 36) with a community, non-dual, aged base RAF weight of 0.166. Under the older CMS-HCC V24 model, E08.641 maps to Diabetes with Acute Complications (HCC 17) with a community, non-dual, aged base RAF weight of 0.302. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
This is a serious complication requiring immediate documentation of treatment provided. Because E08.641 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E08.641 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •This is a serious complication requiring immediate documentation of treatment provided
- •Distinguish from hypoglycemia without coma (E08.649)
Clinical Significance
Diabetes mellitus due to an underlying condition with hypoglycemia with coma represents a severe acute complication where hypoglycemia from insulin or oral hypoglycemic therapy has progressed to loss of consciousness. This is a medical emergency requiring immediate glucose administration and carries risk of permanent neurological damage, cardiac arrhythmias, and death. In secondary diabetes, hypoglycemic episodes may be more unpredictable due to the underlying disease affecting glucose counter-regulation.
Documentation Requirements
- ✓Document the underlying condition causing diabetes, the hypoglycemic event with specific glucose level, coma or loss of consciousness, the precipitating cause (insulin dosing error, missed meal, drug interaction), treatment administered (glucagon, IV dextrose), and neurological status upon recovery.
- ✓Record medication adjustments to prevent recurrence.