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D51.1 ICD-10-CM Code: Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria

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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Nutritional anemias (D50-D53)

D51.1

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria

This is a type of anemia (low red blood cell count) caused by the body's inability to properly absorb vitamin B12 from food, which also results in protein being lost in the urine. The malabsorption of B12 leads to insufficient red blood cell production, causing fatigue and weakness.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

Basket needed

Code Book Path

Official
D51Vitamin B12 deficiency anemia
D51.1Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria

Inclusion Terms

Official
  • Imerslund (Gräsbeck) syndrome
  • Megaloblastic hereditary anemia

Excludes 2

Official
  • deficiency of other B group vitamins (E53-)

Related Child Codes

Official
D51.0Vitamin B12 deficiency anemia due to intrinsic factor deficiency
D51.2Transcobalamin II deficiency
D51.3Other dietary vitamin B12 deficiency anemia
D51.8Other vitamin B12 deficiency anemias
D51.9Vitamin B12 deficiency anemia, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for D51.1 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for D51.1 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D51.1 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D51.1 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D51.1 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Verify documentation specifies both the selective B12 malabsorption AND the presence of proteinuria, as both conditions must be present to use this specific code
Do not use this code if the B12 deficiency is due to other causes such as pernicious anemia, dietary deficiency, or post-gastrectomy; each has its own specific ICD-10-CM code

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D51.1 an HCC code?

No. D51.1 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D51.1 is the ICD-10-CM diagnosis code for vitamin b12 deficiency anemia due to selective vitamin b12 malabsorption with proteinuria. This is a type of anemia (low red blood cell count) caused by the body's inability to properly absorb vitamin B12 from food, which also results in protein being lost in the urine. The malabsorption of B12 leads to insufficient red blood cell production, causing fatigue and weakness. D51.1 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering nutritional anemias (d50-d53).

D51.1 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Verify documentation specifies both the selective B12 malabsorption AND the presence of proteinuria, as both conditions must be present to use this specific code.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D51.1 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify documentation specifies both the selective B12 malabsorption AND the presence of proteinuria, as both conditions must be present to use this specific code
  • Do not use this code if the B12 deficiency is due to other causes such as pernicious anemia, dietary deficiency, or post-gastrectomy; each has its own specific ICD-10-CM code

Child Codes

Code Hierarchy

D51Vitamin B12 deficiency anemiaD51.1Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
D51.1Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria

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