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D21.6 ICD-10-CM Code: Benign neoplasm of connective and other soft tissue of trunk, unspecified

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FY 2026 Apr update / Neoplasms (C00-D49) / Benign neoplasms, except benign neuroendocrine tumors (D10-D36)

D21.6

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Benign neoplasm of connective and other soft tissue of trunk, unspecified

This code describes a benign (non-cancerous) tumor that develops in the soft tissues of the trunk area, such as muscles, fat, or connective tissue, when the specific location cannot be determined. These tumors are not life-threatening but may require monitoring or removal depending on their size and symptoms.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
D21Other benign neoplasms of connective and other soft tissue
D21.6Benign neoplasm of connective and other soft tissue of trunk, unspecified

Inclusion Terms

Official
  • Benign neoplasm of connective and other soft tissue of back NOS

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D21.6 in this effective period.

Related Child Codes

Official
D21.0Benign neoplasm of connective and other soft tissue of head, face and neck
D21.1Benign neoplasm of connective and other soft tissue of upper limb, including shoulder
D21.2Benign neoplasm of connective and other soft tissue of lower limb, including hip
D21.3Benign neoplasm of connective and other soft tissue of thorax
D21.4Benign neoplasm of connective and other soft tissue of abdomen

Includes

Official
  • benign neoplasm of blood vessel
  • benign neoplasm of bursa
  • benign neoplasm of cartilage
  • benign neoplasm of fascia
  • benign neoplasm of fat

Excludes 1

Official
  • benign neoplasm of articular cartilage (D16.-)
  • benign neoplasm of cartilage of larynx (D14.1)
  • benign neoplasm of cartilage of nose (D14.0)
  • benign neoplasm of connective tissue of breast (D24.-)
  • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D21.6 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D21.6 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D21.6 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Use this code only when the exact anatomical site of the trunk tumor is unknown or unspecified; if the location is documented (chest wall, abdominal wall, etc.), use a more specific D21 subcode
Verify documentation to confirm the tumor is benign and located in the trunk region; if malignant or location is clearly specified, different coding would apply

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D21.6 an HCC code?

No. D21.6 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D21.6 is the ICD-10-CM diagnosis code for benign neoplasm of connective and other soft tissue of trunk, unspecified. This code describes a benign (non-cancerous) tumor that develops in the soft tissues of the trunk area, such as muscles, fat, or connective tissue, when the specific location cannot be determined. These tumors are not life-threatening but may require monitoring or removal depending on their size and symptoms. D21.6 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering benign neoplasms, except benign neuroendocrine tumors (d10-d36).

D21.6 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Use this code only when the exact anatomical site of the trunk tumor is unknown or unspecified; if the location is documented (chest wall, abdominal wall, etc.), use a more specific D21 subcode.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D21.6 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use this code only when the exact anatomical site of the trunk tumor is unknown or unspecified; if the location is documented (chest wall, abdominal wall, etc.), use a more specific D21 subcode
  • Verify documentation to confirm the tumor is benign and located in the trunk region; if malignant or location is clearly specified, different coding would apply

Child Codes

Code Hierarchy

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