C82.29
BillableFollicular lymphoma grade III, unspecified, extranodal and solid organ sites
Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)
Is C82.29 an HCC code?
Yes. C82.29 maps to Breast, Prostate, Colorectal and Other Cancers and Tumors under the CMS-HCC V28 risk adjustment model (and Lymphoma and Other Cancers under V24).
HCC Category Mapping
RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
MEAT Criteria for C82.29
For C82.29 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed C82.29 during that encounter — not just copy-forwarded from a problem list.
What This Code Means
C82.29 is the ICD-10-CM diagnosis code for follicular lymphoma grade iii, unspecified, extranodal and solid organ sites. A type of blood cancer (follicular lymphoma) affecting organs outside the lymph node system or solid organs. This is an advanced grade (grade III) of the disease. C82.29 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).
Under the CMS-HCC V28 risk adjustment model, C82.29 maps to Breast, Prostate, Colorectal and Other Cancers and Tumors (HCC 21) with a community, non-dual, aged base RAF weight of 0.545. Under the older CMS-HCC V24 model, C82.29 maps to Lymphoma and Other Cancers (HCC 10) with a community, non-dual, aged base RAF weight of 0.675. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
Identify and document the specific extranodal sites involved (liver, bone marrow, GI tract, etc.). Because C82.29 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C82.29 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Identify and document the specific extranodal sites involved (liver, bone marrow, GI tract, etc.)
- •This code indicates more advanced disease with organ involvement
Clinical Significance
Follicular lymphoma grade III unspecified involving extranodal and solid organ sites represents the most advanced disease presentation — high-grade histology with organ infiltration. This combination frequently involves bone marrow and may overlap clinically with diffuse large B-cell lymphoma. Aggressive treatment is standard, and accurate coding ensures appropriate risk-adjusted resource allocation.
Documentation Requirements
- ✓Pathology confirming grade III follicular lymphoma in extranodal tissue
- ✓All involved extranodal sites documented (bone marrow, liver, GI, skin, etc.)
- ✓Bone marrow biopsy with quantification of involvement percentage
- ✓Organ function assessments for affected organs
- ✓Query for IIIa vs. IIIb and reassessment for DLBCL transformation
Commonly Confused Codes
- •C82.27 — Grade III, spleen; spleen has its own code, not grouped under extranodal
- •C82.28 — Grade III, multiple nodal sites; for multi-site nodal, not organ involvement
- •C83.39 — Diffuse large B-cell lymphoma, extranodal; if transformation from follicular to DLBCL
- •C82.19 — Grade II, extranodal; verify pathology grade before selecting