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C57.3 ICD-10-CM Code: Malignant neoplasm of parametrium

C57.3 maps to CMS-HCC V28 22. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · free HCC coding tools

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Code lookupC57.3

FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of female genital organs (C51-C58)

C57.3

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Malignant neoplasm of parametrium

Cancer that develops in the parametrium, the connective tissue surrounding the uterus that provides structural support.

Buddy the Bee presenting code insight

Buddy Insight

Parametrial cancer involves the connective tissue surrounding the lower portion of the uterus between the layers of the broad ligament.

CMS-HCC V28

HCC 22

Coefficient HCC 22: 0.363 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 011

Code-level coefficient reference

ESRD/PACE

HCC 10

Code-level coefficient reference

RXHCC

HCC 22

Code-level coefficient reference

Inclusion Terms

Official
  • Malignant neoplasm of uterine ligament NOS

Excludes 2

Official

No Excludes 2 notes are included in this display for C57.3. Check the code and parent instructions in the Code Book.

Includes

Official
  • malignant neoplasm of skin of female genital organsInherited from C51-C58

Excludes 1

Official

No Excludes 1 notes are included in this display for C57.3. Check the code and parent instructions in the Code Book.

Code First

Official

No Code First sequencing instructions are included in this display for C57.3. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for C57.3. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for C57.3. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Pathology or imaging confirming parametrial malignancy
Whether the parametrial cancer is primary or secondary to cervical/uterine extension
FIGO or TNM staging
Histologic type and grade

MEAT Support

HCC Buddy guidance
Pathology or imaging confirming parametrial malignancy
Whether the parametrial cancer is primary or secondary to cervical/uterine extension
FIGO or TNM staging
Histologic type and grade

Audit Caution

HCC Buddy guidance
Coding parametrial extension of cervical cancer as C57.3 instead of the appropriate cervical primary code — parametrial extension is a staging element, not a separate primary
Failing to distinguish between primary parametrial cancer and cervical cancer with parametrial invasion
Omitting staging documentation that determines whether parametrial disease represents local extension

Common Mistakes

HCC Buddy guidance
C53.0-C53.9 — Cervical cancer codes; parametrial involvement from cervical cancer is staged differently and coded at the primary cervical site
C55 — Malignant neoplasm of uterus, part unspecified; use C57.3 only when parametrium is specifically identified
C57.4 — Uterine adnexa unspecified; parametrium is a specific identifiable structure
C57.10-C57.12 — Broad ligament cancer; parametrium is within but distinct from the broad ligament

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C57.3 an HCC code?

Yes. C57.3 (Malignant neoplasm of parametrium) maps to HCC 22, Bladder, Colorectal, and Other Cancers under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 0.363. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: C57.3 is billable and maps to V28 HCC 22, Bladder, Colorectal, and Other Cancers. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
C57.3
Description
Malignant neoplasm of parametrium
HCC (V28)
HCC 22 — Bladder, Colorectal, and Other Cancers
RAF reference coefficient
0.363
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 22, Bladder, Colorectal, and Other Cancers
0.363
ESRDHCC 10, Lymphoma and Other Cancers
Not separately weighted
RxHCCHCC 22, Prostate, Breast, Bladder, and Other Cancers and Tumors
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work C57.3 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for C57.3

For C57.3, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

C57.3 is the ICD-10-CM diagnosis code for malignant neoplasm of parametrium. Cancer that develops in the parametrium, the connective tissue surrounding the uterus that provides structural support. C57.3 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of female genital organs (c51-c58).

Under the CMS-HCC V28 risk adjustment model, C57.3 maps to Bladder, Colorectal, and Other Cancers (HCC 22) with a source-labeled community, non-dual, aged reference coefficient of 0.363. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Parametrial cancers are often secondary to uterine cancer; verify if this is primary or extension. For C57.3, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C57.3 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Parametrial cancers are often secondary to uterine cancer; verify if this is primary or extension
  • Document whether cancer is confined to parametrium or extends to adjacent structures

Clinical Significance

Parametrial cancer involves the connective tissue surrounding the lower portion of the uterus between the layers of the broad ligament. Primary parametrial malignancies are rare; most parametrial involvement represents direct extension of cervical cancer (FIGO Stage IIB or higher). Distinguishing primary from secondary parametrial cancer is critical for accurate coding and staging.

Documentation Requirements

  • Pathology or imaging confirming parametrial malignancy
  • Whether the parametrial cancer is primary or secondary to cervical/uterine extension
  • FIGO or TNM staging
  • Histologic type and grade
  • Extent of parametrial involvement (unilateral vs. bilateral, extent to pelvic wall)
  • Active treatment versus surveillance status

Commonly Confused Codes

  • C53.0-C53.9: Cervical cancer codes; parametrial involvement from cervical cancer is staged differently and coded at the primary cervical site
  • C55: Malignant neoplasm of uterus, part unspecified; use C57.3 only when parametrium is specifically identified
  • C57.4: Uterine adnexa unspecified; parametrium is a specific identifiable structure
  • C57.10-C57.12: Broad ligament cancer; parametrium is within but distinct from the broad ligament

Child Codes

Code Hierarchy

Also searched as

  • C57 3
  • C573

For C57.3, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

C57.3 maps to CMS-HCC V28 category 22, Bladder, Colorectal, and Other Cancers. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. The mapping identifies a payment HCC category for C57.3. Review its source-labeled HCC coefficient above, check the RAF Calculator with complete member context for CMS-HCC V28 PY2026, and confirm the documentation the chart needs before the code is submitted. HCC Buddy shows no RAF score unless every required source and calculation check passes.

Work C57.3 in HCC Buddy

Open C57.3 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.